Have access already?

Get access to this chapter:

Or get access to the entire book:

Chapter 52: Parkinson’s Disease

DOI:

10.1891/9780826171481.0052

Authors

  • Hareez, Lana, PharmD, BCPS
  • Pham, Antony Q., PharmD, BCPS

Abstract

Parkinson’s disease (PD) is a neurodegenerative disease with no known cause or cure. Several different kinds of parkinsonism can be mentioned: postencephalic, arteriosclerotic, posttraumatic, secondary to medications, atrophic encephalopathic, and as part of a wider involvement of the nervous system in olivopontocerebellar atrophy and other neurodegenerative diseases. Idiopathic PD is the most common form of parkinsonism. The primary neurochemical lesion of PD results from the deficiency of dopamine in the basal ganglia. Movement disorders result from disease of the basal ganglia. Patients with PD can have other motor impairments in addition to the cardinal symptoms. Nonmotor symptoms can also be debilitating in PD. The treatment of patients with PD requires an interprofessional approach. Primary care providers must work closely with neurology consultants to provide patients with the most advanced interventions.