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Chapter 24: Pancreatitis: Acute and Chronic

DOI:

10.1891/9780826171481.0024

Authors

  • Davanos, EvangeliaSteinberg, Ashley, PharmD, BCNSP, CNSC, MD

Abstract

Pancreatitis, an inflammatory disease of the pancreas, may be classified as acute or chronic. Most cases of acute pancreatitis are caused by either alcohol intake or gallstones. Treatment is largely supportive, with intravenous hydration and parenteral analgesics being the mainstay of therapy. Pancreatic duct obstruction, smoking, hereditary factors, or hypertriglyceridemia may all cause chronic pancreatitis. The pancreas has both endocrine and exocrine secretory properties. The incidence of acute pancreatitis has been steadily increasing over time, negatively influencing the burden on health care costs worldwide. Clinically, abdominal pain, tenderness, and raised serum concentration of pancreatic enzymes are the most common features. Several modalities have been used for pain control in chronic pancreatitis, including transcutaneous electrical nerve stimulation (TENS), acupuncture, and biofeedback. Because the pain is severe, these modalities are used more with chronic pancreatitis than with acute pancreatitis.