The prevalence of cultural elements in trauma-based disorders has been widely neglected in Western evidence-based treatment of immigrant populations. While eye movement desensitization and reprocessing (EMDR) therapy retains a firmly Western character as an evidence-based treatment approach defined by the American Psychological Association (APA), this chapter presents a case report that explores how culturally based trauma in immigrant populations may be addressed in EMDR therapy. The case demonstrates how effective steps for developing a culturally attuned EMDR therapy process allow a holistic focus and culture conscious therapeutic alliance. While an exclusively factual history would focus on the client’s pathology only, this chapter also addresses the cultural identity of the therapist as well as placing emphasis on the communalities and differences in the cultural and historic context of both therapist and client in order to counteract assimilationist implications in the therapy room.