The core human need for social connection and a sense of belonging is depicted along with its relevance and value within eye movement desensitization and reprocessing (EMDR) therapy. The chapter recommends that Connection and Belonging be seen as a distinct category of negative and positive cognitions along with Responsibility/Defectiveness, Safety, and Power/Control/Choice and describes how this addition can be seen as consistent with the teaching of EMDR founder Francine Shapiro. Negative beliefs within this category are presented such as “I can’t connect,” I don’t belong,” “I am alone,” “I can’t be myself,” and “my voice doesn’t matter.” These and other negative beliefs within this category often have high resonance with regard to socially and culturally based trauma and adversity and capture the experience of those suffering with loneliness. The chapter discusses social information processing as it enhances the Adaptive Information Processing (AIP) model. Later sections of the chapter show the wide recognition of the need for social connection and belonging within psychology including Maslow’s hierarchy of needs, attachment theory, and Relational Cultural Theory.