Nursing research provides the scientific bases for practice, and nurses are interested in finding the most effective approaches to achieving and sustaining optimal patient-centered care. To help determine the credibility and usefulness of research to practice, this chapter provides basic guidelines for reviewing and critiquing quantitative and qualitative research reports. It focuses on assessment of research quality. In research, quality is defined as the extent to which a study has minimized bias in the selection of participants, measurements, and external factors that may have an impact on the study's results. The chapter emphasizes the role of nurses' use of research as a component of evidence-based practice to answer practice questions, solve problems, enhance the quality of patient care, and shape important healthcare decisions. It reviews basic terms and provides checklists and suggestions that support nurses in the appraisal of research prior to translating the research into practice.