This chapter provides an overview of planned change management to facilitate implementation of evidence-based practice (EBP) in the clinical setting. It presents two change scenarios. In Scenario 1, implementation of practice change related to interprofessional simulation was ultimately unsuccessful. In contrast, Scenario 2 illustrates a successful practice change initiative in which the approach to the proposed initiative was deliberate and systematic to ensure adoption in a dynamic and demanding practice environment. Lewin's three-step change model and force field analysis along with Kotter's change management principles frame the discussion about this EBP organizational initiative. Using change theory to guide systematic implementation of EBP helps bridge the research-practice gap by providing a guiding framework to implement and achieve sustained change. Participation of staff in the change effort from the onset as well as maintaining open and ongoing communication throughout the change process are essential to minimize resistance and promote sustainable, permanent change.