Heart failure (HF) is a burdensome population health issue. In the United States alone, there are over 5.7 million patients diagnosed with this disease. Currently, HF is accountable for greater than 80% of healthcare dollars attributed to treatment costs and is a considerable burden to the healthcare system. There are nonmodifiable and major modifiable risk factors that can be addressed in order to prevent this disease in specific populations. Rural America accounts for one fourth of the total population of the United States and this population has the lowest access to care. Nurses are challenged to provide quality care to these areas. Through the use of telehealth, prevention, and risk assessments, nurses can improve health outcomes of populations with HF, especially in rural areas.