This chapter describes how simulation fits the needs for 21st-century nursing education. It covers the aspects include the changing needs for nursing education in a technologically complex environment, how to succeed when incorporating simulation, the importance of the faculty role in embedding simulation throughout the nursing curriculum, meeting the challenges of clinical placement, and specific challenges and benefits to integrating simulation into the curriculum with an evidence-based practice focus. Simulation provides the missing piece for nursing education through harnessing each student’s enthusiasm for technology into an interactive and valuable learning experience in which to engage in critical thinking (Radhakrishnan, Roche, & Cunningham, 2007). Simulation takes on a life of its own, thus becoming "real" to the students. In conclusion, this chapter has emphasized the importance of integrating a simulation-focused pedagogy throughout the curriculum to best meet the needs of our program.