Women who have disabilities face many challenges that, in combination, can have a unique impact on workforce entry, career decision-making, and employment outcomes. In light of these direct outcomes and the critical roles that work can play in alleviating poverty and increasing quality of life, this chapter adapts a client-focused considering work model to highlight the barriers to work for women with disabilities; discuss ways to assess these barriers; and provide a framework for evaluating the considering work process and incorporating varied interventions to address the unique psychosocial, financial/legal, vocational, and medical barriers to employment for women with disabilities. The chapter provides a broad overview of the demographics of women with disabilities. The client-centered considering work model provides a solid framework for exploring and assessing the career decision-making process for women with disabilities.