Simulation-based education is recognized as a powerful tool in addressing patient safety and quality care training for healthcare providers. Simulation is increasingly used as effective learning method, especially in the area of healthcare. Simulation is rapidly becoming an essential and effective strategy in nursing education, providing a controlled and safe environment for learning. This chapter is dedicated to the simulation team, including administrators, managers, simulation staff, simulation operators, and ancillary personnel who are charged with the day-to-day responsibilities of running a simulation center to effectively meet the training needs of advanced practice registered nurse (APRNs) and interprofessional teams. This chapter includes entries on administrative considerations including developing policies, procedures, accreditation, training of essential personnel, setting up and maintaining equipment, technology considerations, acquiring proper consents for video recordings, and supporting the simulation staff in obtaining the Certified Healthcare Simulation Operations Specialist certification.