This chapter summarizes the theory of moderated guiding, discusses the methodological decisions that influenced the research process, and highlights significant issues. It provides a summary of key points a researcher may wish to consider when designing a study. The main concern of nurses in end-of-life care was different expectations. This was managed using the process of moderated guiding, which included the sub-processes of checking out, which referred to informational understanding and potential alternatives; involving that comprised conversational maneuvering and negotiating choices; and supporting, which included deliberating and safeguarding. In the theory of moderated guiding, participants were chosen because they could talk about nursing practice in end-of-life care. The research began with interviewing nurses in hospices, aged care facilities, and hospitals. The critical issue is the researcher’s willingness to learn from experience and his or her commitment to produce a scholarly piece of work.