Ongoing project support is a crucial part of any global health venture that involves any hope for long-term, sustainable effects. Developing a specific strategy for ongoing support at the inception of a global health endeavor will involve defining the overall life span and specific stages of the project and budgeting for appropriate resources and personnel to support all stages, even those when minimal contact is planned with the target country or population. Ongoing project support often involves monitoring and evaluation that can potentially be used to answer research questions. Evaluation is an important aspect of all project-based work not only for improved project performance, but also to demonstrate results for funders. This chapter presents two case studies, one on the interprofessional partnerships with a telehealth project in Waslala, Nicaragua and the other on the use of technology to support an ongoing partnership for nursing education in Uganda.