Many people, including nurses, assume that living and working in an area that is considered multicultural or culturally diverse automatically makes them culturally astute or competent. In clinical competency, there are many models for working within cultures, yet cultural safety and cultural competence are learned skills like any other clinical competency. Working within cultures is a dynamic process, and building bridges within cultures is a skill set that should be honed. The chapter provides a case study of Aboriginal peoples in Canada to illustrate the building of bridges within cultures. It also presents a case study that illustrates how Aga Khan University School of Nursing (AKUSON) has transformed the face of nursing education and empowered women in the developing world by heavily investing in faculty development.