The author, Carol A. Cartwright, had the privilege of leading Kent State University and Bowling Green State University public research universities for nearly two decades. In these roles, and in the other leadership posts within academe that preceded them, she have witnessed and experienced the inextricable link between personal development and professional progress. Her leadership path challenges the common perception that successful leaders are born, complete with the requisite temperament and talents. She accepted a faculty position at The Pennsylvania State University. A colleague who observed her in various meetings noted that she had leadership potential and encouraged an intentional exploration of leadership opportunities. Self-knowledge is a psychological prerequisite for effective leadership in general and for leading change in particular. It is nothing less than essential for current and aspiring nurse leaders who want to help transform health care in ways that benefit society and the nursing profession.