Roughly 47 million individuals live with major and mild neurocognitive disorders (NCDs) worldwide. The DSM-V and assessment scales area used in the diagnosis of NCDs. Neuropsychological and neurological testing can also be utilized to identify NCDs syndromes. These assessment tools include, but are not limited to, the Mini Mental Status Exam, the Montreal Cognitive Assessment and the six-item cognitive impairment test. Lastly, both nonpharmacological and pharmacological are available in managing cognitive, mood, and behavioral symptoms related-to NCDs. This chapter helps the practitioners to: identify basic neurological changes in the geriatric client; discuss screening tools that can be used to establish a neurocognitive disorder diagnosis; define major and mild neurocognitive disorder; identify neurocognitive disorder subtypes; discuss basic etiology of neurocognitive disorder subtypes; identify and assess patients for symptoms corresponding to neurocognitive disorders; demonstrate basic understanding of pseudodementia; and recommend general pharmacological and non-pharmacological interventions for neuropsychiatric symptoms related to neurocognitive disorders.