This chapter presents three case studies on restless legs syndrome (RLS), insomnia and hypersomnia. If RLS is left untreated, psychosocial issues and problems with activities of daily living can occur. The food and drug administration has given approval to a device to help with the symptoms of RLS. A Task Force of the International Restless Legs Syndrome Study Group (IRLSSG) has developed evidence-based guidelines for long-term pharmacologic treatment of RLS. Often older people tend to become sleepier in the early evening and wake earlier in the morning compared to younger adults. This pattern is known as advanced sleep phase syndrome. Evidence-based practice supports some complementary therapies that have been effective based on objective sleep measures. The standard nonpharmacological approach to insomnia focus on: stimulus control, sleep restriction, sleep hygiene, sleep environment improvement, relaxation training, remaining passively awake and biofeedback. Obstructive sleep apnea may be a contributing factor for hypersomnia.