Stereoelectroencephalography (SEEG) is rapidly becoming popular in pediatrics because of its minimal invasiveness, decreased blood loss, favorable tolerability, versatility, and compatibility with minimally invasive treatment options such as stereotactic ablation and neuromodulation. SEEG has increasingly become a standard method of intracranial investigation in pediatric epilepsy surgery, and in some centers is generally preferred over traditional placement of grids and strips. Despite the advantages, SEEG can present certain technical challenges in children. Appropriate preoperative workup, appreciation for limitations, careful planning, attentive head fixation, judicious use of general anesthesia, and heightened caution during electrode implantation are all critical to successful pediatric SEEG. This chapter discusses special considerations that should be taken into account in the pediatric population when considering and performing SEEG. Performing SEEG in children warrants careful attention to technical issues, including skull thickness/density, anesthesia risk, head growth, behavioral planning, perioperative antiepileptic drug management, and workflow planning.