Nurses have a key role in the identification, treatment, and control of the transmission of infection within the correctional setting. The prevalence of infectious disease among the incarcerated has great impact on the safety and security of correctional facilities and on the public health. Nursing interventions that prevent communicable diseases such as ectoparasites, Human Immunodeficiency Virus, Methicillin-Resistant Staphylococcus aureus (MRSA), Sexually Transmitted Infections (STIs) include screening, patient education and counseling, immunization, monitoring treatment compliance, and symptom management. Handwashing, or hand hygiene, is arguably the best overall workplace practice for preventing spread of infection. Isolation procedures are used to control transmission of disease when treating patients with known or suspected transmissible infections. Nursing procedures involved in prevention and control of communicable diseases include medication administration, monitoring inmate adherence to the treatment plan, education, counseling to reduce risk of disease transmission, collaboration with public health organizations, and discharge planning.