This chapter explores how effective project management (PM) techniques can guide improvement in health care quality, safety, and patient outcomes. It defines project management and explores the key concepts. In today's health care environment, every health care member is responsible for and contributes to quality improvement (QI) translation and sustainability. The chapter introduces the nurse as an integral interprofessional team member and discusses how frontline workers are crucial in QI projects. Using PM techniques increases QI project success. The PM techniques include the five phases of initiating, planning, executing, monitoring, and controlling, and closing. The chapter defines each phase and also demonstrates how the nurse answers a current health care problem using PM techniques. It discusses leadership and management characteristics required during PM and then highlights nursing leadership skills central to managing interprofessional teams and QI projects. Finally, the chapter examines PM benefits and limitations.