In hospice, the nurse case manager must be able to integrate case management skills with their expertise in end-of-life care. In this way, the hospice nurse case manager assures that the complex care required by hospice patients and families is delivered seamlessly. The complex needs of hospice patients necessitate interventions by multiple professionals. Yet, the hospice Registered Nurse (RN) is responsible for assessing the multidimensional needs of each patient on admission and on an ongoing basis. The nurse also coordinates care with other disciplines and helps to identify social, psychological, and spiritual needs as well as physical needs. Thus, in many home care hospice settings, the RN serves as a case manager. This chapter helps the nurse to describe the role of the case manager and explains how the hospice case manager contributes to quality patient care. It discusses the duties of the hospice nurse case manager.