This chapter describes the problem of missing children along with its assessment; diagnosis; levels of prevention/intervention; primary, secondary, and tertiary strategies for dealing with the behavior; and parenting tips. Children, especially children with autism, may wander, while others may run away, become lost in unfamiliar places or during disasters, or be abducted. Most missing children leave of their own accord, usually because of an adverse family situation; others are thrown out of their families, and many of these are not reported. About one third of this group runs away from foster care. When these children are gone for prolonged periods of time, they become at risk for medical and psychological problems, as well as crime as they may be subjected to human trafficking and drug trafficking. Children may also be abducted by neighbors and other acquaintances. Most nonfamily abductors are male, and most victims are female.