Although assisted living administrators do not serve as clinicians to older persons within their facility, understanding normal psychological changes related to the aging process allows administrators to perform their work more effectively. Understanding many of the normal aging-related changes in neurological functioning, mental health functioning, memory, and cognition can be important in understanding how elders function in assisted living communities. Furthermore, issues related to memory changes, dementia, depression, suicide risk, alcohol, and substance abuse can be commonly experienced by the elderly. An awareness and understanding of these issues can be beneficial to assisted living administrators. Many individuals associate memory changes and problems as an inherent part of the aging process. This chapter identifies and presents best practices in selected areas associated with psychological aspects of aging. Best practices can provide administrators with information and examples of strategies for approaching some of the psychological issues present in aging individuals.