This book emphasizes the importance of sleep across states of health, health care settings, and at all stages of human development. It uses an evidence-based approach to synthesize and integrate nursing and interdisciplinary research on sleep to serve as a foundation for curriculum, teaching, practice, and researchactivities. The book is divided into four units. Unit I addresses aspects of normal sleep, including normal sleep physiology and behavior and developmental and gender aspects. In Unit II, the book provides an overview of the importance of sleep and its consequences from an epidemiological perspective, extant sleep-related nosologies, and a guide to sleep assessment. Unit II also discusses the epidemiology, consequences, assessment, and treatment of the sleep disorders such as insomnia, sleep-related breathing disorders including central sleep apnea (CSA), parasomnias, narcolepsy and circadian rhythm disorders (CRD), and psychaitric and pediatric disorders, the health disparities associated with sleep disorders, and provides an overview of complementary and alternative therapies for sleep. Unit III focuses on integration of the clinical research on sleep into specific settings where many nurses work (occupational health, primary care, acute care, long-term care, psychiatric settings, pediatric primary care, pediatric acute care, and maternal-child health). In Unit IV, the book presents suggestions about ways to integrate sleep and sleep disorders into pre-licensure and graduate nursing education, ideas about the future of nursing practice related to sleep, and proposed directions for future research.

This book is meant to be a practice resource for a medical-surgical nurse and guides the nurse through the most common conditions seen on the medical-surgical unit. It covers assessment, key clinical skills/procedures, and documentation of care in an easily digestible, bulleted format. Clinical chapters organized by body system for easy reference present common conditions seen in medical-surgical nursing and unit emergencies, along with focused assessments and PQRST system, lab work overview, related procedures and skills, a documentation guide, and common medications including those for pain management. The medical conditions and emergencies and their treatments discussed in the book are: neurological deficits, cardiac events, respiratory emergencies, gastrointestinal conditions, genitourinary alterations, wound infection, hip fracture, and endocrine disorders. Chapters also cover pre-operative and post-operative care for all conditions. Evaluation of level of consciousness (LOC) and mentation are the most important parts of the neurological exam. The final chapter is a must-have resource guide, including common pain scales; calculation guides; documentation scales for blood pressure, edema, and pulse; intramuscular technique hints; fall and restraint reduction guides; prevention of central line infection; syringe-size guides; intravenous solution review; intake and output guide.

This book provides a state-of-the-art overview of the principles of cancer care and best practices for restoring function and quality of life to cancer survivors. Cancer rehabilitation interventions including physical, occupational, or speech therapy; exercise training; psychosocial and cognitive interventions; and physician-directed diagnostic imaging, injections, and pharmacologic symptom management have the potential to treat many impairments from cancer treatment, thereby improving functioning and quality of life. Multimodal rehabilitation interventions have also been shown to improve return to work compared to usual care. The chapters of the book review the latest evidence about which interventions should be used to treat specific impairments thereby constituting the most comprehensive and up-to-date reference on this topic. The book is organized into nine parts comprising 90 chapters. Part one presents history of cancer rehabilitation, cancer statistics, and principles of cancer care. Part two discusses various cancer types, which includes breast cancer, gastrointestinal malignancies, head and neck cancer, pediatric cancers, and primary bone tumors and their assessment and management. Parts three through six describe cancer pain, medical complications, neurological and neuromuscular complications, and musculoskeletal complications of cancer such as radiculopathy, plexopathy, autonomic dysfunction, and bone metastases and their management. Part seven discusses general topics related to cancer rehabilitation, which includes physical and occupational therapy, therapeutic modalities in cancer, therapeutic exercise in cancer, nutritional care of the cancer patient, sexuality issues, and distress and other psychiatric considerations in cancer rehabilitation. Part eight thoroughly explores the identification, evaluation, and treatment of specific impairments and disabilities that result from cancer and the treatment of cancer such as balance and gait dysfunction, cancer related fatigue, radiation fibrosis syndrome, and bowel dysfunction. Part nine discusses functional measurement in patients with cancer, health maintenance and screening in cancer survivors, research issues, barriers to accessing cancer rehabilitation, and building a cancer rehabilitation program.

This book is a response that fosters education, practice development, and professionalism. The bachelor of science in nursing (BSN) is the essential educational foundation to give nurses the knowledge to improve health outcomes and provide the highest quality care. It provides the essentials of nursing theory and the importance of having a philosophy of nursing that informs our professional role. The book is written to assist with the transition from the role of the LPN to the baccalaureate-prepared registered nurse (RN). Licensed practical nurses (LPNs) who enter a university to advance their education through seeking a baccalaureate of nursing degree often find the experience of socializing into the new professional role challenging. The book analyzes the change process, discusses Benner’s stages of clinical competence, examines the philosophy of nursing and describes stress reduction measures. The terms leadership and management are described, and the role of the baccalaureate-prepared nurse as leader and manager is explored. Finally the book talks about the Skill Competencies required for the Baccalaureate-Prepared Nurse-electronic health records (EHRs); the Technology Informatics Guiding Education Reform (TIGER) Movement; Simulated E-Health Delivery System (SEEDS) and Nursing Informatics Education Model (NIEM). The Quality and Safety Education for Nurses (QSEN) program was created in 2005 by an expert panel of nursing educators with the aim of preparing future nurses to continuously advance the quality and safety of the health care system in which they practice. The group developed six core competencies to be incorporated into nursing curricula: client-centered care; teamwork and collaboration; evidence-based practice; quality improvement; safety; and informatics.

The goal of this book is to teach the ability to form an autonomous and clinically useful opinion about any 12-lead electrocardiogram (EKG). It introduces basic principles of anatomy and physiology, including a review of the heart’s electrical system. The heart has an intricate electrical system, made up of highly specialized cells, that is responsible for generating each heart beat. The heart’s electrical system consists of five structures: the sinoatrial (SA node), the atrioventricular (AV node), the bundle of His, the right and left bundle branches, and the Purkinje fibers. One of the most basic yet important pieces of information the EKG provides is the heart rate (HR). The most accurate way to measure heart rate is by measuring the R-R interval. Learning the normal electrical direction of forces in the heart provides a simple and scientific way of understanding and interpreting an EKG. The book also discusses vital elements of cardiology, such as atrial and ventricular arrhythmias, conduction abnormalities and heart block, ischemic and nonischemic disorders, and more. It explains various types of heart blocks such as premature atrial contraction, sinus arrest and asystole, and various types of pacemakers such as ventricular pacemaker and artrial pacemakers. Drug effects and toxicities, electrolyte imbalances, trauma, pericardial diseases, lung disease, cancer, cardiomyopathies, and systemic diseases are conditions that can cause specific changes on the EKG.

This book details the technical aspects of how to achieve requirements for clinical treatment planning aspects, including patient positioning, creation of patient specific bolus, beam angle configurations, and inverse planning optimization approaches. It is written for everyone involved in treatment planning including dosimetrists, physicists, and physicians. The book comprises of 14 chapters. The first three chapters are introductory chapters. Chapter one describes the types of treatment plans and the general process of treatment planning. The second chapter explains the principles and limitations of current inverse planning optimization algorithms, and discusses the application of auto-planning, knowledge-based planning, and multi-criteria optimization to overcome these limitations. The third chapter covers the available immobilization equipment and general principles of simulation, including patient safety procedures. Chapters four through eleven are organized by body site or system and covers central nervous system, head and neck, breast cancer, thoracic cancer, gastrointestinal radiotherapy, genitourinary cancer, gynecologic cancer, lymphoma, and soft tissue sarcoma. For each site, there is a description of patient simulation, including immobilization, setup, isocenter placement, and any special considerations such as motion management. The plan goals for each treatment site are tabulated, followed by recipes to achieve them from the simplest planning technique to the most advanced planning technique. For simple 3D conformal plans, the recipes include the field arrangement and portal shape design (both with many figures), beam weighting, and selection of dose normalization point. For advanced techniques such as intensity-modulated radiation therapy, volumetric modulated radiation therapy, and stereotactic body radiation therapy, the recipes provide details of creation of optimization structures and multiple stage optimizations. Each chapter concludes with plan evaluation, comparing achieved doses to the clinical planning goals. Chapter thirteen describes treatment planning for pediatric cancers. Chapter fourteen discusses treatment planning for palliative treatment.

This book is designed for nurses who are beginning to work field of pediatrics, and can be a great asset to the novice nurse who is orienting to the unit, or even to the student nurse who is beginning a clinical rotation in the specialized area of pediatric nursing. It presents suggestions on how to communicate and work with children using age-appropriate techniques. The book is divided into three parts. Part I deals with the pediatric principles with chapters highlighting the tips for working with children, discussing immunizations, preventive care and anticipatory guidance for the well child care. Physical examination and reporting child abuse are also described. The role of the pediatric nurse is focused in the second part, which discusses health care delivery and hospitalization. The nurse’s role in medical administration is also explained in this section. Part III reviews the common pediatric disorders such as emotional or behavioural disorders, neurologic and chromosomal disorders, skin disorders, respiratory disorders, cardiovascular disorders, blood and lymphatic disorders, gastrointestinal disorders, genitourinary disorders and muscoskeletal disorders. The book ends with a discussion on communical diseases of childhood.

This book is meant to educate and assist any healthcare professional who has the privilege of caring for patients with acute stroke. Although it is particularly helpful for clinicians who are involved with critical decision making, practitioners at all levels of training can use the book as a guide. The practice of stroke medicine has become quite complex over the past two decades. Fortunately, this is for good reasons. The intricacies associated with management of ischemic and hemorrhagic strokes reflect improved understanding of the disease process, advances in neuroimaging, and development of novel treatment options. In the first 24 to 72 hours of hospitalization, stroke patients are susceptible to a whole host of cerebral (neurological) and extracerebral (medical) complications. Being familiar with these complications and having the knowledge to properly identify and manage them can reduce length of hospital stay, adverse functional outcomes, and mortality. This book hopes that practitioners will appreciate acute stroke management as a dynamic process and understand the uniqueness of acute stroke as a clinical entity with its potential for complications that may be a direct or indirect consequence of the initial brain injury. The book consists of fifteen chapters. Chapter one provides an introduction to complications of acute stroke. Chapter two discusses cerebral ischemic infarction. Next three chapters focus on expansion of intracerebral hemorrhage; cerebral edema in stroke; and post-thrombolysis hemorrhage and hemorrhagic transformation of cerebral infarction. Chapters six and seven discuss endovascular and postprocedural complications and reperfusion injury in ischemic stroke. The next two chapters focus on stroke-related seizures, rebleeding, vasospasm, and hydrocephalus after subarachnoid Hemorrhage. Chapter ten describes the complications of cerebral venous thrombosis. The following four chapters discuss complications after stroke such as delirium, cardiac complications, pulmonary complications, and metabolic complications. The last chapter briefly describes poststroke infections.

Since its recognition as a subspecialty in 2005, the neurocritical care community has significantly grown. An increasing number of hospitals across the United States provide subspecialized neurocritical care, and fellowship-trained neurointensivists are in demand more than ever. This book is intended to be a comprehensive study guide and self-assessment tool for candidates sitting for both initial certification and recertification in neurocritical care. In addition, trainees taking the surgical or medicine critical care boards will also find it useful as it covers the neurocritical care component of their board curriculums. The book is an easy-to-read, concise yet comprehensive, and portable learning resource not only for board preparation, but also for medical students, residents, and fellows rotating in the neurocritical care unit. Nurses, advance practice providers, and non-neurointensivist physicians who participate in the care of neurocritical care patients will also find this book to be an easy guide to the management of many frequently encountered issues, with case examples and imaging to further guide their education. The chapters are named and arranged in a similar format to the board curriculum to allow for easy review and organization when studying for the boards. The question-and-answer (Q&A) format allows the reader to perform thorough self-assessment prior to taking the exam. The answers are detailed and cover the majority of the board syllabus with updated references for additional reading. The book covers the key topics pertinent to (and found on) neurocritical care boards, and is organized according to the exam core curriculum outline. The questions address both neuroscience critical care (general neurology, neurotrauma, neurovascular and neurosurgical problems) and general critical care topics (systems trauma, cardiovascular, infectious disease, pulmonary and renal issues, and hemodynamic monitoring).

This book focuses on key elements a healthcare practitioner needs to know to evaluate and manage multiple sclerosis (MS)and related neuroimmunological disorders. Information on disease history, pathophysiology, and biology are included to provide clinicians with a framework for understanding current diagnosis, monitoring, and treatment strategies for these disorders. In addition to reviewing disease-modifying treatments, the book focuses on frequent symptoms of MS and their treatment options. Assessment tools and treatment options for symptom management and rehabilitation have also evolved and become increasingly complex. Wellness promotion and patient-centered care are among the growing care strategies than can and should be applied to the management of MS. The goal of the book is to put together in one readily readable volume the core information that guides day-to-day care in an MS center. Each chapter is an amalgam of evidence-based data with experience-based guidance, combining the science and art of MS and related disease management. The authors present the approaches to care that they use in their centers. Where applicable, the authors provide lists of “Key Points” for clinicians as well as “Key Points” for patients and families. These highlights make the “gist” of each chapter clear and immediately available, and also provide a short summary that can be shared with patients. Critical-to-know information and management pearls are pulled out from the text and boxed for quick reference throughout the book. Illustrative cases are included in chapters where appropriate to amplify clinical recommendations. The authors made every effort to update the most recent medication changes, recognizing that this is a very fast changing field and we anticipate new medications in the near future. With this edition they have completed revised chapters on disease-modifying therapies, since there has been tremendous progress in this area.

This book discusses important topics that have come to the forefront of medical rehabilitation and disability, covering disabling conditions and disorders not only from clinical but also functional and psychological perspectives. It provides comprehensive guides on what to expect and how to manage each medical issue, discussing the causative agents, classification, pain management, psychological factors, and much more. The book is divided into three parts. Part I presents an introduction to key topics and issues. The second part offers discussions on several disabling conditions and disorders. The medical conditions/disorders discussed include AIDS and HIV infection, Alzheimer’s disease, traumatic brain injury, burn injuries, cancer, cardiovascular disorders, chronic pain syndromes, diabetes, epilepsy, hematological disorders, developmental disabilities, neuromuscular disorders, neuromuscular disorders, musculoskeletal disorders, pediatric disorders including cerebral palsy, and limb deficiency. Part III presents some special topics such as adult medical speech-language pathology, social work, telerehabilitation, and assistive technology.

This book concentrates on board-related concepts in the field of Rehabilitation Medicine. It will appeal to medical students, residents, and practicing physiatrists. Residents will find the book essential in preparing for Part I and Part II of the Physical Medicine and Rehabilitation (PM&R) Board Certification because it is one of the only books of its kind with major focus on board-related material giving a synopsis of up-to-date PM&R orthopedic, neurologic, and general medical information all in one place. Over 500 diagrams simplify material that is board pertinent. The topics are divided into major subspecialty areas such as stroke, traumatic brain injury, musculoskeletal medicine, electrodiagnostic medicine, prosthetics and orthotics, spinal cord injuries, physical modalities, pulmonary, cardiac, and cancer rehabilitation, pediatric rehabilitation, and pain medicine. All chapters are authored by physicians with special interests and clinical expertise in the respective subjects. Board pearls are highlighted with an open-book icon throughout the text. These pearls are aimed at stressing the clinical and board-eligible aspects of the topics. The content is modeled after the topic selection of the American Academy of Physical Medicine and Rehabilitation Self-Assessment Examination for Residents (SAE-R) Content Outline. This was done specifically to help all residents, post graduates in yearly preparation and carryover from the SAE preparation to board exam preparation. Practicing physiatrists should also find this book helpful in preparation for the recertifying exam.

This book describes innovative, nurse-managed solutions for improving health care today. It addresses the key business, policy, medical, financial, and operational considerations necessary for successfully opening and operating nurse-led health facilities. With the mission to dramatically expand access to primary and preventive health care, these clinics provide a full range of services including primary care, health promotion, disease prevention, and behavioral health care to residents of underserved communities throughout the United States. The book provides a historical perspective on nurse-managed health centers (NMHCs), includes chapters on the practical aspects of starting and operating NMHCs, combined with case studies that illustrate the challenges, lessons learned, and successes of NMHCs, and deals with an assessment of the current status of NMHCs and a vision for their future. The book delivers a wealth of comprehensive information for nurses who are considering opening their own clinics. Reinforced with best-practice models and case studies, it discusses what it takes to successfully start and run a nurse-managed health center. The book addresses the history and growth of nurse-led clinics and describes the nurse-led paradigm of care. It identifies the different types of nurse-led clinics (primary care, school based, wellness, and more) and the clinical services offered within them. Also discussed are the requirements and mind-set of potential consumers and strategies for sustainability along with the role of the collaborative team. The pros and cons of a variety of business and operations models are examined along with quality metrics and initiatives. The book also covers various state and federal policy challenges and opportunities and explores the future of nurse-led care in view of ongoing health care reform.

This book presents readers with the essential aspects of the subspecialty infectious diseases. The second edition of the book includes new developments that are consistent with the published peer-reviewed medical literature and published relevant clinical practice guidelines. The book’s intended audiences are students and medical providers in training. It provides information evolved from prior formal didactic lectures or bedside clinical teaching on clinical infectious diseases, microbiology, and antimicrobial pharmacology that was delivered to help students, residents, fellows, and primary care physicians. Current basic science and clinical concepts regarding each relevant infectious disease topic are still written as a synoptic account to make these topics clear and practical for the readers. The book is organized into 18 parts containing 52 chapters. It adheres wherever possible to a standard pattern of description that aims to define the topic and provide an introduction that would include classification, pathophysiology, and epidemiologic information. The book also lists relevant causative microorganisms; describe the clinical aspects and approach to the topic with the physical examination and relevant laboratory methods, diagnostic imaging, and appropriate antimicrobial therapy. The first part provides introduction to clinical reasoning, antimicrobial stewardship, antimicrobial agents, and medical microbiology. The remaining parts describes the approach to various topics such as: fever of unknown origin, leukocytosis, bloodstream and cardiovascular infections, pulmonary infections, gastrointestinal infections, hepatobiliary infections, hepatic infections, renal–urinary infections, neurological infections, orthopedic-related infections, skin and soft-tissue infections, sexually transmitted infections, infections related to obstetrics and gynecology, eye infections, sepsis, transplant-related infections, ectoparasite-related infections, and infection control and epidemiology. The book’s goal is to help guide the reader through the diagnostic evaluation as well as the process of caring for the patient with an infection.

This book is a clinically relevant reference guide for health care trainees, medical providers, and active allied health professionals who work with patients and clients suffering from all aspects of insults to the brain. Not limited to traumatic brain injuries, the book provides easy-to-follow formatting by providing information involving all aspects of acquired injuries to the brain and related clinical outcomes. Each chapter provides an overview of a subtype of brain injury, accompanied by history, pathophysiology, etiology, epidemiology, clinical presentation, other diagnostic considerations, treatment, prognosis, and clinical synopsis. Stroke is an enormous public health problem as it is one of the leading causes of both death and disability worldwide. Stroke symptoms, with very few exceptions, begin with the sudden onset of focal neurological deficits, which are confined to a vascular territory. Treatment of stroke can generally be divided into three categories: acute stroke management, rehabilitation, and secondary stroke prevention. Acquired brain injury (ABI), at any age, is a significant public health concern. It is particularly problematic in the elderly considering the increased rates of mortality and morbidity following ABI in this population. Optimal rehabilitation of ABI requires a multidisciplinary approach of trained rehabilitation specialists at appropriate timing and with appropriate intensity. Brain injury rehabilitation requires a comprehensive treatment program to reduce impairments and to restore function, participation, and quality of life. Useful case studies are also provided for most conditions described in the book.

This book attempts to build students’ understanding of policy development through a critical analysis and review of policy frameworks, and the policy implementation process. The book is organized into four parts comprising twenty-one chapters. Part one of this book lays out a background as to the current and future demographic trends of older adults and makes the case for the reader that there are a variety of philosophical, political, economic, and social factors that affect public policy development. The chapters help the reader to explore a range of perspectives that define, shape, and impact the development and implementation of public policy. It intends to prepare the reader to critically analyze public policies related to aging. Part two provides an overview to major federal policies and programs that impact older adults and people with disabilities. It examines some historical developments leading up to the actual development and implementation of the policies. Policies include social security, medicare, the Older Americans Act, and the Americans with Disabilities Act, the Community Mental Health Centers Act, and Freedom Initiative. The last part of the book outlines specific programmatic areas that flow from aging policies, and specific components that flow from federally mandated policies. Each chapter contains same basic outline: an overview of the programs, specific features and strengths of the programs, gaps and areas for development, and challenges for the future.

Stereo electroencephalography (EEG) has become the predominant method across the world to invasively explore patients with focal epilepsy who are potential candidates for resective surgery. This required many epilepsy centers to introduce major workflow adaptations, investment in surgical and imaging technologies, and seek training in placement and interpretation of depth electrodes recordings. It became evident that a comprehensive, practical textbook outlining the different steps and nuances of the methodology was missing. This book covers all practical aspects of stereo EEG and is a quintessential staple for anybody learning and working in the field of epilepsy surgery, including adult and pediatric epileptologists and neurophysiologists, functional neurosurgeons, technologists, and trainees in these areas. The book is a complete and practical guide to thinking and doing stereoelectroencephalography (SEEG) which will be a solid reference to practitioners around the world. Almost all chapters feature illustrative cases to explain specific aspects and key concepts of the SEEG methodology. The section covering the practical approach to specific epilepsy syndromes includes voice-over slide presentations demonstrating the process of a systematic patient discussion, hypothesis generation, and electrode planning followed by data interpretation and delineation of surgical resection. The book starts with the historical background and principles of stereo EEG and discusses the role of the noninvasive evaluation and patient selection. It describes technical aspects of electrodes, multimodal data coregistration, and guidelines for invasive monitoring. The book then presents the conceptual framework of stereo EEG followed by surgical aspects of stereo EEG electrode placement covering robotic and frame-based approaches, specific pediatric aspects, and potential complications. It describes data interpretation of physiologic, interictal, and ictal epileptic activity, and outlines conceptual and methodological aspects of electrical stimulation mapping. The book ends with discussing surgical procedures to remove the epileptogenic zone and a review of seizure and cognitive outcome with stereo EEG.

This book presents theoretical underpinnings of perinatal and pediatric bereavement, chapters on dimensions of perinatal and pediatric loss that have been of interest recently, and clinical interventions derived from research. It is divided into two sections. The first section has 10 chapters focusing on aspects of perinatal loss. It presents background content on various grief theories developed in the past five decades. These theories have expanded our understanding of the processes of death, dying, and bereavement. Grief after pregnancy loss can be more complicated for certain groups. The book provides a comprehensive overview of perinatal grief among lesbian couples and an overview of perinatal loss in adolescents, discussing normal adolescent growth and development, and using Sanders’s integrated theory of bereavement to discuss the common physical, emotional, social, and cognitive reactions to loss. The second section has eight chapters focusing on various aspects of caring for families whose children are dying or who have died, and caring for children who are grieving. Sometimes, the death of a child can occur under traumatic circumstances, setting the stage for very intense psychological responses. The book focuses on the impact of the cause of the death on posttraumatic stress responses and overall parental health after the traumatic loss of a child and describes supportive interventions for bereaved parents. Suicide is one of the most traumatic losses a family can experience. Finally, the book presents the importance of creating and capturing meaningful moments in the time leading up to and after the death of a child, focusing on the importance of relationships among families and professionals as they prepare for the child’s death.

This book focuses on common mental illnesses and weaves both the psychodynamic and neurobiological concepts into evidence-based strategies for nursing interventions. It provides information on descriptive psychiatric diagnoses, quality and safety education for nurses (QSEN) criteria, and NANDA-based care plans, case scenarios, evidence-based practice, patient and family education tips, drug summary lists, and complementary and alternative therapy approaches. The book also provides new information on psychopharmacology, compassion fatigue and a recovery model, use of informed consent, and cognitive behavioral therapy. Psychiatric-mental health nursing care is practiced in multiple settings across the health care continuum. Patients of all ages in need of psychiatric-mental health nursing care can be found in hospitals, community agencies, and residential settings. Critical thinking and clinical decision making are crucial elements to ensure that the patient’s needs are assessed, relevant problems are identified, and therapeutic nursing interventions are planned, implemented, and evaluated. Clinical decision making based on critical thinking is similar across all clinical settings. One unique dimension of critical thinking in psychiatric-mental health nursing is the importance of the interpersonal relationship as a major healing factor in delivering psychiatric nursing care. The book focuses on how psychiatric nurses integrate the concepts of critical thinking, clinical decision making, and the nursing process within the interpersonal relationship to address patient needs and delivery of nursing care.

This book covers all dimensions of palliative care but with a special emphasis on primary palliative care. The book is organized into three parts comprising twenty two chapters. Part one provides the essential background and principles of supportive oncology and palliative care, including chapters on understanding the adult and pediatric patient and family illness experience, the roles and responsibilities of the palliative care team, and the art of the palliative care assessment interview. Part two covers symptom management and includes ten chapters considering the major physical and psychosocial symptoms a cancer patient may face—neurologic, cardiac, respiratory, gastrointestinal, genitourinary, psychiatric, sleep and fatigue, pain, and psychosocial and spiritual distress. Part three addresses special considerations and issues that an oncologist, physician, nurse or other healthcare provider often face in these settings, including chapters on intimacy, sexuality, and fertility issues, grief and bereavement, running a family meeting, care for the caregiver, and survivorship.

The Society for Immunotherapy of Cancer (SITC) has expanded efforts to respond to the exponential growth of educational needs by offering primers at the Annual Meeting, itinerant courses to health care providers domestically and internationally, topical meetings and task forces addressing salient questions related to the field, specifying guidelines for patient toxicity management, policy and quality benchmark development, and informing on other themes as they emerge through the SITC portal. In this context, SITC leadership decided to update, refine, and broaden the legacy established by the first edition of this textbook by providing a second edition that targets primarily young basic and clinical investigators but is informative to as many other constituencies as possible. The new edition of Cancer Immunotherapy Principles and Practice updates chapters of the first edition while introducing new ones to cover emerging concepts. Chapters for textbooks can be painstakingly overbearing, but all contributors managed to complete their part to bring together cutting-edge insights that every translational investigator and practicing clinician needs to know about tumor immunology and immunotherapy. The textbook is divided into five sections: Basic Principles of Tumor Immunology, Cancer Immunotherapy Targets and Classes, Immune Function in Cancer Patients, Disease-Specific Treatments and Outcomes, and Regulatory Aspects of Cancer Immunotherapy. These sections cover the continuum from basic principles to practical and clinically relevant information to allow critical understanding of the development and testing of novel therapeutics, companion diagnostics, and useful biomarkers, and inform about the regulatory processes that support the safe and efficient delivery of immunotherapy to patients with cancer. In addition, the chapter on the history of immunotherapy was not only preserved but updated to honor and recognize those who pioneered and championed the field.

As the field of intensive care unit (ICU) electroencephalogram (EEG) monitoring evolves, the use of continuous EEG monitoring (cEEG) is expanding beyond seizure detection. EEG provides continuous and noninvasive monitoring of brain function and, coupled with quantitative EEG, enables clinicians to monitor for signs of acute and evolving cerebral injury. Early identification of these electroencephalographic biomarkers may, in turn, offer targets for therapeutic neuroprotective interventions. This book provides a contemporary and concise summary of important principles ranging from seizure identification and encephalopathy grading to advanced techniques of quantitative EEG and multimodality monitoring. These principles are important for current clinical care and advancement of the field. It includes 12 core chapters, each of which begins with text, tables, and figures and ends with a series of EEG images illustrating the concepts and principles discussed in the text. Each chapter is written by experts in the field. In addition, case-based approaches to common scenarios focus on EEG pattern recognition, diagnostic evaluation, and management. The cases not only build upon EEG skills learned in the chapters but also cover additional diagnostic and management principles. The book also includes chapter-based board-style multiple-choice questions and videos available online to elucidate important concepts. This atlas will benefit an audience ranging from novices to experts in the fields of neurology, epilepsy, neurophysiology, neurocritical care, neonatology, and cardiac and pediatric critical care medicine.

Head and neck cancers are challenging diseases that require complex management and exemplify the value of collaboration among multiple specialties. Very appropriately, the Editors are representatives of each of the three major treatment modalities. The genesis of this work was driven by recognition that, despite evolution in various approaches and new emerging data, high quality clinical care is optimal when there is mutual respect of each other’s discipline, and when each patient has a treatment recommendation made by multidisciplinary input. When discussing the need for a new textbook the authors recognized and agreed that critical developments have been transforming the field of head and neck oncology. Indeed, in the past few years there have been significant advances in our understanding of the molecular biology, immune evasion, and genetic landscape of head and neck cancers, as well as the multidisciplinary management of these malignancies, including immunotherapy, targeted therapies, precision radiation therapy, robotic surgery, and supportive care capabilities. With the rising epidemic of human papillomavirus-associated oropharyngeal cancer, customizing treatment is of utmost importance, in particular taking into consideration long-term treatment effects. This book captures key advances and aims to become a quick and handy reference tool for head and neck cancer management issues, and features didactic patient cases in each site-specific management chapter. The authors anticipate that physicians involved in the care of these patients will find the material relevant to their clinical practice. Evidence-based approaches are emphasized throughout the textbook. The book consists of four sections. The first section discusses epidemiology, biology, diagnosis, and staging. The second section deals with established and emerging treatment modalities of head and neck cancers. The third section discusses site-specific management. The fourth section deals with recurrent or metastatic disease and the last section discusses supportive care and special patient groups.

The field of stem cell transplantation has evolved dramatically over the past decade. Improvements in supportive care and the use of targeted therapies after transplant to prevent relapse have improved the outcome for patients undergoing autologous transplantation. This modality of therapy remains an important therapeutic option for patients with myeloma and relapsed lymphoma. The limitations of donor availability for allogeneic transplant has been largely eliminated with improved molecular typing for unrelated donors and the increasing use of alternative donor stem cell sources, such as haploidentical donors and umbilical cord blood. The safety of allogeneic transplantation has improved by the routine assessment of a patient’s comorbidities and the tailoring of the transplant intensity to achieve the best outcome. This handbook discusses a number of diseases in detail. The chapters give the reader an increased understanding of the disease and the options for therapy. It also allows the reader to understand the role of either transplantation or cellular therapy in the context of disease risk and other therapeutic options. The handbook provides a resource to clinicians caring for patients undergoing transplantation or receiving cellular therapies. Fellows, interns, residents, students, advanced practice professionals in nursing and physician assistants, and pharmacists, as well as others in the care of these patients, may find this handbook useful. The book describes the role of transplantation or cellular therapies in a variety of hematologic malignancies. There are chapters addressing complications related to infections, liver dysfunction, renal dysfunction and pulmonary complications. Special emphasis is given to both acute and chronic graft-versus-host disease and their management. Finally, there is an important chapter on the long-term management of patients after transplantation, which should be of help to all providers who care for survivors of transplantation.

In this comprehensive and clinically directed reference for the diagnosis and treatment of persons with spinal cord injury (SCI) and related disorders, the editors of the two leading texts on SCI medicine have joined together to develop a singular premier resource for professionals in the field. Spinal Cord Medicine, Third Edition, draws on the expertise of seasoned editors and experienced chapter authors to produce one collaborative volume with the most up-to-date medical, clinical, and rehabilitation knowledge in SCI management across the spectrum of care. This jointly configured third edition builds on the foundation of both prior texts to reflect the breadth and depth of the specialty. The book covers assessment, acute injury management and surgical considerations, medical management, neurological and musculoskeletal care, rehabilitation, recent research advances, system-based practice, and special topics. New and expanded content focuses on the significant changes in the epidemiology of traumatic injury, the classification of SCI, and the latest medical treatments of multiple complications, as well as new surgical considerations in acute and chronic SCI and the many advances in technology that impact rehabilitation and patients’ overall quality of life.

This book provides us with what we need to sleep well. It provides the tools and techniques to reverse insomnia and improve sleep long-term. Insomnia, persistent trouble getting to sleep or staying asleep, affects our daytime functioning and wellbeing. The book breaks down the principles of cognitive behavioral therapy for insomnia (CBT-I), the sleep program considered first-line treatment in the clinic, into a step-by-step and reader friendly program that can be easily followed at home. Written by a clinical psychologist and researcher who has worked in the sleep field for 40 years, the book uses data from a real patient to illustrate each step of the process. The book is complete with detailed sleep diaries, worksheets, and more, all of which are also available online to download and use on your own journey to sleeping better now and into the future. Guiding readers through this self-directed sleep therapy program, the book features updated information and new scientific findings on key topics for patients and health care providers including: tried-and-true CBT-I methods of sleep management; successful cognitive therapy methods to deal with racing thoughts at bedtime; different sleep needs for women and men through life and health conditions; influence of nutrition, exercise, and sex on sleep in a brand-new chapter; depression, anxiety, and traumatic stress and how they intersect with sleep; and prescribed and non-prescribed medications, herbal remedies, and cannabis for sleep.

Sports medicine practitioners' primary responsibility is to provide optimal medical care for athletes on and off the field. The care continuum for the athlete includes injury/illness prevention, diagnosis, treatment, rehabilitation, and return to sport. Prompt evaluation of an injured athlete on the field can expedite the diagnostic process, management, rehabilitation, and return to sport, frequently the most important outcome measure. The understanding of basic concepts related to sports coverage will help the practitioner provide high level care. This handbook provides a unified resource that covers the knowledge gaps that may be present when providing sports coverage. It is divided into several sections. The Introductory section covers common topics that apply to all sports medicine practitioners providing sideline or event coverage independent of level of experience. For example: the role of the team medical provider; what to have in the medical bag; factors to consider when traveling with a team; medicolegal issues specific to the medical team member; how to assess and manage common medical emergencies; nutrition and hydration recommendations for pre-, during, and post-training or competition; preparticipation physicals; general concepts of adaptive sports; and lastly, general concepts of doping in sports. The further sections dive into sport-specific coverage divided by contact, limited-contact, or no-ncontact sport classification. The book also covers summer and winter Olympic sports and other popular sports that are practiced worldwide. It provides information on the history, participants, rules and regulations, equipment needed and/or required, medical coverage logistics, emergencies, medical bag essentials, epidemiology, and a brief discussion of common injuries for each individual sport. The book will serve as an excellent resource for physicians in training or seasoned veterans from all specialties, athletic trainers, physical therapists, and any other healthcare providers who want to provide on-field, sideline, or event sports coverage.

The complexity of current practice in pediatric neurology can be daunting to individuals who are new to the field. Within the last several years, clinical neuroscience has progressed at a staggering pace with more and more sophisticated brain imaging and physiological monitoring techniques, a deeper understanding of the genetics and molecular mechanisms of many diseases, and increasingly specific treatment options for many disorders. We are now able to effectively diagnose and treat many diseases that until recently would have been beyond our reach. Such exciting developments call for an accessible review of this complex topic. Pediatric Neurology: Clinical Assessment and Management is designed for trainees and nonspecialists looking for concise and targeted information on diagnosis and treatment of neurological conditions in children. The book provides an introduction to clinical pediatric neurology and neuroscience with chapters written by pediatric neurologists from top national institutions, many of whom have made major contributions to the development of the field. The chapters emphasize key information and patient care concepts for novice learners to provide a broad window on the primary neurological disorders of children and current approaches to recognition and management. This book is not intended to be a comprehensive text, but rather a starting point for individuals who wish to delve into this exciting area and for practitioners in other disciplines who need to know basic concepts.

The goal of the electromyographer is to localize lesions and to characterize them. In order to accomplish these goals, a minimum core of knowledge in neuroscience is required. This book discusses that core of neuroscientific knowledge as a stepping stone to lesion localization and characterization. Following this, it demonstrates how this information is actually utilized in the electromyography (EMG) laboratory using a case study approach. Although several excellent EMG case study-based textbooks are available, the book is unique in that it offers a step-by-step analysis of the nerve conduction studies (NCS) and needle EMG studies as they are collected, including a discussion of the initial studies required based on the presenting clinical features, an interpretation of those initial studies, and the indications for subsequent studies based on that interpretation. This step-by-step analysis continues until the lesion has been fully localized and characterized. The book is extensive and explains the important principles and concepts underlying electrodiagnosis (EDX) medicine. It reviews the anatomy and physiology of the peripheral neuromuscular system, basic principles of NCS, specific concepts pertinent to each type of NCS (motor, sensory, and mixed NCS, as well as repetitive nerve stimulation studies), and the basic principles of needle EMG. Following this, it discusses the NCS and needle EMG measurements made, their meaning, and the EDX manifestations of the various neuromuscular disorders. It also includes a discussion of the various types of nerve injuries and a review of reinnervation. It focuses on lesion localization and the characterization of the lesion, including its pathology, pathophysiology, severity, and temporal features. The book demonstrates the application of the principles and concepts through 60 EDX case studies collected from the authors' EMG laboratories using a step-by-step analysis format.

The purpose of this handbook is to create a practical guide for trainees, nurse practitioners, physician assistants, and attending physicians to guide them in the treatment of patients with gastrointestinal cancers. The handbook provides key information on diagnosis and treatment, while highlighting the epidemiology, molecular data, and additionally various multimodality treatment options for a broad array of gastrointestinal cancers. It is concise and easy to read, yet broad and practical in its ability to provide for the needs of the medical professional dealing with gastrointestinal cancers. Unique to the book are “How I Treat” vignettes providing not only standards of care but expert recommendations for approaching tough-to-treat disease sites and, in some cases, rare or uncommon patient scenarios. The book is appropriate for physicians in all specialties as well as primary care physicians and other healthcare professionals who are essential members of any team caring for the patient with gastrointestinal cancer. It begins with the most common of the gastrointestinal cancers, colon and rectal cancer, followed by pancreatic, hepatocellular, esophageal, and gastric cancer, cancer of the bile ducts and gallbladder, and then the more rare and unusual cancers such as gastrointestinal stromal tumors, neuroendocrine tumors, and anal carcinoma. In each of these sections, the authors use evidence-based guidelines for the specific cancer to focus on epidemiology and biologic aspects of the disease, including genetic factors and molecular biology. Chapters also discuss modifiable factors, diagnostic testing, and techniques consisting of the molecular basis of diagnosis and treatment of early and advanced disease, which incorporates the role of surgery, neoadjuvant and adjuvant chemotherapy, radiation therapy, immunotherapy, and biologics and their selection and ablative techniques. The presentation is very helpful and unique in that the authors approach advanced disease as oligometastatic and widely metastatic and account for how these approaches differ.

This book serves as a practical and useful guide for the multidisciplinary management of long-term cancer survivors. It consists of 16 chapters that are organized into two sections. Section 1: Foundations of cancer survivorship care covers basic principles of survivorship that aids the clinician in the assessment and management of survivors' care. Chapters 1 and 2 introduce the reader to core concepts of survivorship; provides a review of the Institute of Medicine core domains; and present a definition of cancer survivorship and long-term cancer survivors. Chapter 3 provides a detailed discussion of the basic concepts of surveillance, late effects, and prevention of new or secondary cancers. Chapter 4 outlines the psychologic challenges that often accompany the survivorship experience. Strategies for cancer screening and prevention are discussed in Chapter 5 with application to the needs of long-term cancer survivors. Chapters 6 and 7 focus on the complex care of older survivors, ≥ 65 years and provides a useful discussion of late effects and comorbid conditions which create a confluence of special needs for this population. Chapter 8 discusses the role of integrative medicine in addressing some of the late effects of cancer and its treatment. The book is designed for care of the adult survivors; however, Chapter 9 addresses the burdens faced by adolescent and young adults who are survivors of cancer. Section 2: survivorship care and management for selected disease sites focuses on cancers selected by editors because they were the sites with the largest number of survivors seen in the clinics or are considered the most common in long-term survivors. Chapters 10 to 16 offer guidance on surveillance, prevention, late effects, and psychosocial issues encountered by cancer survivors. Brief clinical vignettes illustrate the application of the clinical practice algorithm(s) and survivorship care plan developed for each type of cancer.

As the field of medical oncology evolves, the authors have developed a new format for the 3rd edition of this textbook, now titled: Tumor Board Review: Evidence-Based Case Reviews and Questions. The text includes recent advances in the diagnosis and treatment of the most common malignancies encountered by oncology providers. It also includes recently published clinical studies and updated cancer guidelines. Further, the authors discuss the importance of genetic mutations in selection of anticancer drugs (e.g., Braf mutations in melanoma) based on phase III clinical trials in both solid tumors and hematological malignancies. The content of this 3rd edition represents authors’ best effort to incorporate and highlight the most recent clinically relevant data in our field. The authors continue to use a case-based format, but they present each oncologic disease type in a tumor board format with a brief synopsis of a patient case followed by a discussion of the imaging and molecular and/or genomic sequencing required for a correct diagnosis. Each chapter finishes with a dialogue on staging and treatment including chemotherapy, immunotherapy, and targeted agent regimens. Finally, the text closes with pertinent information related to follow-up and survivorship. Each chapter includes up to ten board style questions at the end to help the reader enhance his/her/their knowledge base. The third edition continues to represent a joint effort between oncology faculty and subspecialty fellows based at the Baylor College of Medicine (Houston, Texas), the University of Michigan Medical School (Ann Arbor, Michigan), and the University of California Davis Medical Center (Sacramento, California).

This edition of the Handbook of EEG Interpretation promises to be the best iteration yet. Each chapter is written by a professor of neurology subspecializing in the field of epilepsy. As in any field of medicine, the best quality of care evolves and is reflected by new knowledge borne by the practitioner. In the case of electroencephalography (EEG), this knowledge is a function of exposure and of experience. Hence, the book hopes to fill a void that exists by providing quick and easy access to topics in EEG in the hopes of ultimately providing better patient care. The book reviews abnormal nonepileptiform EEG. In addition to the chapter on abnormal epileptiform EEG, these are foundational chapters necessary to provide an accurate clinical correlation and facilitate appropriate patient management of patients with seizures and neurological illnesses that may have management decisions predicated upon interpretation of EEG. The book summarizes pediatric seizures and the role of ambulatory EEG, in addition to video-EEG and adult seizures, new chapters to emphasize the increasing role of event recording with EEG. The chapter on sleep provides a focus on and correlation of patients with sleep disorders and epilepsy. The chapter on neurointensive intraoperative monitoring, adds very instructive information to performing a variety of monitoring techniques in the operating room, in addition to a chapter on electrocorticography, to expand on examples that involve patients with epilepsy, brain tumor, vascular malformations, and other diseases of the cerebrum. The excellent final chapter, magnetoencephalography, includes examples to illustrate the powerful source localizing capability of this technique. With completion of the third edition of the handbook, it is the authors hope that it will continue to serve clinicians young and old, experienced and novice, physician and technologist alike.

While there are several comprehensive textbooks on movement disorders, all are lengthy, thick, hardbound books and thus are less useful for the busy, practicing clinician who often needs a quick guide on the diagnostic approach and therapy for various movement disorders. There are a few practical, therapeutic handbooks on Parkinson disease but there are none for other types of movement disorders (chorea, dystonia, myoclonus, ataxia, etc). The ever busy clinician will also benefit from a “primer” on DBS—its new device types, indications, identification of ideal and non-ideal candidates, and trouble-shooting. This third edition is a practical yet authoritative guide to the diagnosis and work up, and the pharmacological, non-pharmacological and surgical treatments of all types of movement disorders for the clinician-intraining and the practicing clinician. The authors used an “expanded outline bullet point” format, with liberal use of flow charts, algorithms and tables, with emphasis on clinical presentation, work-up and management, rather than pathophysiology and disease mechanism. In summary, this book should provide a comprehensive and practical approach to the neurological, behavioral, and surgical treatment of movement disorders. Because the authors anticipate that clinicians may be reading this book comprehensively, from start to finish; or, using it “on demand” by quickly surveying specific chapters related to the phenomenology of a challenging patient—content overlap has been intentional, to emphasize concepts and principles in diagnosis and management. Several movement disorders can present with different phenomenologies, thus several disorders will reappear in various chapters. From the first to this latest edition, the authors aim has always been to empower the modern clinician with the necessary skills in making the evaluation of movement disorders less intimidating and more rewarding.

This book provides a one-stop guide to the essential basic and clinical science of all the effective, life-prolonging drug therapies in oncology. From traditional cytotoxic agents to targeted genomic, epigenomic, hormonal, and immunotherapeutic agents, this book covers the staggering advances in cancer pharmacology that are propelling new standards of care for common and uncommon malignancies. Each chapter contains visually engaging figures detailing the tumor microenvironment, chemical structures of agents, pharmacodynamics, pharmacokinetics, pharmacogenomic, and molecular properties of the various agents, and their mechanisms of action. As the first illustrated book of its kind, this highly visual text uses a uniform approach to each cancer drug class and agent presented in the book, and covers alkylating agents, antimetabolites, antimitotics, epigenetic modulators, hormonal agents, targeted therapies, monoclonal antibodies, immunotherapeutic agents, and much more. Flow diagrams, clinical tables, and bulleted text further explain important information pertaining to each cancer drug class including their indications, mechanisms of action, potential adverse reactions, dosing and dose adjustments, and safety monitoring.

The practice of Pediatric Rehabilitation Medicine (PM&R) is diverse from one country to another, one region to another, one medical center to another and one provider to another. This book covers these diverse areas of practice, whether the care is provided to patients in a large metropolitan tertiary care center, a smaller medical referral center in a less-populated city, or a truly rural practice where the pediatric physiatrist is often the first specialty physician to encounter the child with a disability. The textbook is intended for use by medical providers of all types and especially students, residents, fellows, and busy practicing clinicians within or in close quarters of our specialty of PM&R. The sixth edition of the book provides eight new chapters devoted to Brachial Plexus Palsy, Oncology, Robotics, Genetics, Spasticity Management, Rheumatology, Burns, and Advocacy and significantly expanded coverage of Acquired Brain Injury. These chapters reflect the growth and expansion of the field as medical science evolves, new diagnoses appear, and technology advances at an astounding pace. The thought of powered orthotics and exoskeletons with robotic arms and legs would have been almost impossible to conceive even a decade ago. The book brings in new ideas, many new authors and chapters, and updated material to reflect current evidence-based thinking and practice.

Preparation for board examinations can be a daunting and an overwhelming process for many of us. Trainees are often busy with research projects, manuscripts, and a large clinical volume, making it difficult to find time to study for board examinations. Practicing physicians find it hard to keep up on material needed for board recertification. Questions on the board examinations are drawn from well-established, validated medical literature and widely accepted clinical guidelines. This book provides a comprehensive overview of the field of radiation oncology. The format has been designed to efficiently test and reinforce knowledge of key concepts, critical studies, and major clinical guidelines, with the most important radiation oncology citations included. From trainees preparing for their board exams to practicing physicians looking for a review or preparing for the maintenance of certification exam, whether it be a few minutes between patients or a dedicated study session, the book will an invaluable resource to the radiation oncology community. The book is organized into ten chapters. It covers oncology topics such as head and neck cancers, central nervous system cancers, breast cancer, thoracic cancers, gastrointestinal cancers, genitourinary cancers, gynecologic cancers, lymphomas, soft tissue sarcoma, and pediatric cancers. Each chapter has detailed questions covering natural history, epidemiology, diagnosis, staging, treatment options, and treatment-related side effects all in a newly configured format.

Bone stress injury (BSI) represent an overuse injury to bone seen in athletes and active individuals. Despite being a common injury seen in clinical practice, there exists confusion on multiple aspects of this injury, including appropriate terminology. For example, “stress fracture” is often used interchangeably with “stress reaction” or “stress response”. Recent scientific discoveries on the topic of bone stress injury have advanced our understanding of risk factors for injury. Rarely can the injury be attributed solely to training errors. While training volume, intensity, and frequency do influence bone remodeling, most BSI are multifactorial and involve a combination of biological, anatomical, and biomechanical risk factors for injury. Recognizing risk factors for BSI may help to develop a comprehensive treatment plan to address each injury. Further, the goal of treating the injury should focus on methods to optimize bone health and develop strategies for future injury prevention. This book is organized to address aspects of clinical diagnosis, rehabilitation, and prevention. The authors invited experts across a range of topics to provide a more complete understanding of the full spectrum in BSI treatment. Initial chapters focus on evaluating injury, including the role of the clinical examination and imaging to guide treatment. Recognition of risk factors for BSI are separated into biological and biomechanical risk factors, including gender, age, and anatomical location. The book reviews methods to optimize treatment in each section by anatomical location, and reviews strategies for refractory injuries in designated chapters on medications, emerging technologies, and interventions. Further, the authors identify what is known about future injury prevention and methods to optimize bone strength. The goal of this book is to provide a comprehensive understanding of BSI that improves clinical outcomes and provides a patient-centered treatment program.

Botulinum toxin (BoNT) therapy involves as much art as it does science. Prescription and injection of a BoNT product requires that clinicians be familiar with the unique properties of each product, including its dosage range for a seemingly ever-expanding list of approved or published medical indications. This quick reference guide provides detailed dosage information for the four BoNT products available in the USA (abobotulinumtoxinA, incobotulinumtoxinA, onabotulinumtoxinA, and rimabotulinumtoxinB) which are approved for both cosmetic and medical indications. Included in this abbreviated manual are updated regulatory agency approved medical indications for both adults and children and recommended dosage ranges in the USA (Food and Drug Administration), Canada (Health Canada), the United Kingdom (Medicines & Healthcare products Regulatory Agency), and the European Union (European Medicines Agency). Detailed BoNT dosage information for each of these BoNT products is presented in an easy-to-navigate table format. The tables are organized by clinical indication along with each agency-approved dosage where available and the published dosage ranges per treatment session and per structure injected. Providing this information in a single reference manual allows clinicians to quickly calculate the dosage of a given BoNT product for a given indication and/or structure. The anatomical illustrations provided in this manual serve as a reference guide for clinicians to enhance the localization of muscles and other target structures during the injection planning process. The authors hope this information will be useful for clinicians and for the patients to whom they provide care.

This revised and updated second edition of Handbook of Hematologic Malignancies continues to be an essential and “go-to” resource for the busy hematologist, hematologic oncologist, hematopathologist, oncology advanced practice provider, oncology nurse, and trainee. Hematologic malignancies and their treatment have witnessed many changes in this past decade. Innovations from improved diagnostics to therapeutics have reshaped the ways in which these diseases are characterized and managed. This book highlights critical differential diagnoses to consider as well as provides the most current prognostication tables for each disease in order to facilitate direct extension of this information to the patients. In addition, it includes full-color pathology images that have been selected for their exceptional clarity to help the reader elucidate subtle morphologic differences between disease entities. Concisely organized, each chapter provides the most current, need-to-know points of diagnosis, prognosis, therapeutic management, and clinical trial opportunities for each hematological malignancy. The authors have created relevant clinical cases not only in the book but also in accessible online cases, supporting each chapter with corresponding questions to highlight important deliverables from every chapter. The book provides evidence-based algorithms guiding treatment recommendations for both frontline and salvage settings, with key references supporting each recommendation. The authors’ intention was to create a reference textbook that is concise and easy to read, serving the needs of the medical professional dealing with hematologic malignancies. They highlight current clinical trials that may alter our future practice decisions. Notably, in this 2nd edition, they not only provide major updates and insight into future practice-changing clinical trials but add numerous chapters, particularly those focused on novel cellular immunotherapy, which has been the most exciting revolution in the clinical care of patients with hematologic malignancies.

Handbook of Spasticity is the essential reference for residents and practicing physicians in the fields of physical medicine and rehabilitation and neurology. It allows readers to learn the fundamentals of spasticity management while also adding important spasticity concepts to their day-to-day practice. This high-yield resource provides current evidence-based treatment paradigms and discusses advances in the field to address assessment, treatment options, and disease management in adult and pediatric patients. Written by experts from institutions around the world, this valuable handbook fuses the fundamentals of spasticity with a case-based approach to enhance learning for those early into their career as well as practicing physiatrists, neurologists, nurses, physician assistants, and therapists. Assessment and evaluation measures are detailed, focusing on measurements and scales, gait assessment, and techniques for setting appropriate goals. A wide variety of treatment options are explored, including physical therapy, pharmacologic and nonpharmacologic treatments, emerging technologies, toxins, surgical options, and more. Complete with accompanying online videos, ultrasound and anatomical figures, and toxin dosing tables.

This book describes a collaborative effort by the students, staff, and faculty at the University of New Mexico School of Medicine who worked to create a different approach to medical education—the Primary Care Curriculum (PCC). It is important to compare PCC with other programs to determine what elements in the implementation of problem-based learning are universal, and what elements are unique to PCC. Consequently, each chapter of the book illustrates various approaches to its topic with examples from select programs. After the first chapter on the inception of PCC and other key programs, each chapter will begin with a statement of the specific goals toward which a problem-based learning curriculum should strive. The PCC experience, in attempting to achieve these objectives, will then be presented with an analysis of successes and failures and a summary of the main points learned over the years. The curriculum should stimulate the student’s self-directed learning. Problems should be developed which introduce students to core scientific concepts deemed appropriate for that phase of study. The tutorial groups should provide an environment for the accomplishment of the several goals including self-directed learning and clinical reasoning and problem-solving. In many of the problem-based medical schools, the ability of students to identify and utilize appropriate learning resources including libraries is an established component of student assessment. Chapters also cover clinical skills, community preceptorship, and student performance with respect to problem-based learning. Finally, the book traces the processes whereby PCC, as an innovation in medical education, moved from an experimental to an accepted successful local program at the University of New Mexico.

Clostridium Botulinum is a spore-forming gram-positive rod that is commonly found in soil and water. It produces a toxin called botulinum neurotoxin (BoNT) which is one of the most potent toxins known to mankind. Christian Andreas Justinus Kerner published the first case of botulism in 1817 and called it “sausage poison”. He noted that it paralyzed the skeletal muscle function and the parasympathetic nervous system and proposed its use as a therapeutic agent in neurological diseases characterized by involuntary movements. This book is intended to be used as a quick and accessible reference for injectors during the course of their clinical practice. As practitioners of chemodenervation themselves, the authors have been looking for an up-to-date, uniform resource in a convenient format which is ultimately what lead them to writing this pocketbook. The inclusion of visual and textual information for executing injection localization and suggested dosing for the four commercially-available toxins makes this book a unique, one-stop resource. The author’s goal is that both novice and experienced injectors may use this pocketbook as a practical and evidence-based tool in the course of planning and executing injections As educators, this book will serve as a visual adjunct to bedside teaching. The authors of this book are all directly involved in educating medical trainees in the evaluation and management of spasticity. Despite a robust spasticity curriculum and hands-on experience, we still felt a need for a physical resource to help residents and fellows during the course of their training and as they started their careers. For novice injectors and medical trainees, performing botulinum toxin injections can seem daunting. The authors hope is, that with the use of this book, knowledge can be consolidated into an accessible format, allowing providers to reinforce and sharpen previously learned skills.

This book has been designed to be a high-speed review—a last-minute gut check before the C-EFM^® exam day. The authors created this review, which is a quick summary of the key topics one”ll encounter on the exam, to supplement their certification preparation studies. They encourage the readers to use it in conjunction with other study aids to ensure they are as prepared as possible for the exam. This book follows the National Certification Corporation’s (NCC) most recent exam content outline. It uses a succinct, bulleted format with sample electronic fetal monitoring (EFM) tracings to highlight essential knowledge. The aim of the book is to help the readers solidify their retention of information in the month or so leading up to their exam. It is written by certified nurse practitioners who are familiar with the exam and the content one need to know. Special features appear throughout the book to call out important information, including the following: Complications: Problems that can arise with certain patient conditions or procedures; Nursing Pearls: Additional patient care insights and strategies for knowledge retention; Alerts: Need-to-know details on how to handle emergency situations or when to transfer care; Pop Quizzes: Critical thinking questions to test ones’ ability to synthesize what they learned; and List of Abbreviations: A useful appendix to help guide us through the alphabet soup of clinical terms. Chapters cover maternal and fetal physiology, internal and external fetal monitoring equipment, fetal assessment methods, EFM pattern recognition, fetal and maternal complications, ethical and legal issues, and more.

Focusing on patient-driven chief complaints, this resource provides a wealth of concise information covering each body system along with first-line questions, assessments, and interventions to determine the patient’s level of urgency, sick versus not sick. Prominent icons denote critical signs and symptoms and deliver invaluable information from experienced triage/ED nurses. Content encompasses triage, waiting room and legal issues, high-risk medical conditions, and special issues in emergency care. Including action steps to aid in prioritizing during a crisis, the resource covers trauma, burns, active shooter/active threat, and emergency management during a disaster. Reference tables and checklists facilitate at-a-glance retrieval of crucial information. Opportunities for customization include space for taking notes, inscribing important phone numbers, and pasting facility-specific policies/procedures.

This book was designed to be a high-speed review —a last-minute gut check before the exam day. The authors created this review, which is a quick summary of the key topics one’ll encounter on the exam, to supplement to their certification preparation studies. They encourages the readers to use it in conjunction with other study aids to ensure they are as prepared as possible for the exam. This book follows Competency & Credentialing Institute’s (CCI®) most recent exam content outlines, and uses a succinct, bulleted format to highlight what one need to know. The aim of this book is to help one solidify their retention of information in the month or so leading up to their exam. It is written by certified perioperative nurses who are familiar with the exam and the content one need to know. Special features appear throughout the book to call out important information, including: complications: problems that can arise with certain disease states or procedures; pearls: additional patient care insights and strategies for knowledge retention; alerts: need-to-know details on how to handle emergency situations or when to transfer care; pop quizzes: critical-thinking questions to test our ability to synthesize what we learned; unfolding scenarios: case studies that develop over the course of the chapter to challenge our critical -thinking skills; and list of abbreviations: a useful appendix to help guide us through the alphabet soup of clinical terms. We know life is busy. Being able xto prepare for our exam efficiently and effectively is paramount, which is why the authors created this book. One have come to the right place as they continue on their path of professional growth and development. The stakes are high, and the authors want to help us succeed.

This book was designed to be a high-speed review—a last-minute gut check before the exam day. The authors created this review, which is a quick summary of the key topics one’ll encounter on the exam, to supplement to their certification preparation studies. They encourages the readers to use it in conjunction with other study aids to ensure they are as prepared as possible for the exam. This book, written by certified critical care nurses, follows the American Association of Critical-Care Nurses’ (AACN®) most recent exam content outline, and uses a succinct, bulleted format to highlight what one need to know. It will help the readers solidify their retention of information in the month or so leading up to their exam. Special features appear throughout the book to call out important information, including: complications: Problems that can arise with certain disease states or procedures; pearls: Additional patient care insights and strategies for knowledge retention; Alerts: Need-to-know details on how to handle emergency situations; pop quizzes: Critical-thinking questions to test your ability to synthesize what you learned; medication tables: Handy tables at the end of each body system chapter highlighting the indications, mechanisms of action, contraindications, and adverse effects of commonly administered medications; and list of abbreviations: A useful appendix to help guide us through the alphabet soup of clinical terms. We know life is busy. Being able to prepare for our exam efficiently and effectively is paramount, which is why the authors created this book. One have come to the right place as they continue on their path of professional growth and development. The stakes are high, and the authors want to help us succeed.

Every nurse cares for patients facing end-of-life issues at some point in their career. For some nurses, working with terminally ill patients is an infrequent, yet important experience. For others, it is part of their daily nursing work. Fast Facts for the Hospice Nurse: A Concise Guide to End-of-Life Care, Second edition, like the first edition, is a valuable, up-to-date resource for all nurses whether they work with terminally ill patients on a daily basis or only occasionally. This book is for nurses who are seeking to specialize in hospice, those who work in long-term care settings, postacute care settings, acute care setting, and those who are seeking to enhance their knowledge of end-of-life care within other specialties. This second edition has been thoroughly revised, updated, and expanded. New information has been added on the role of the hospice nurse as case manager, cultural issues, such as working with members of the LGBTQ+ community, and special communication considerations, such as working with deaf and hard of hearing patients and those who have limited English proficiency. In terms of symptom management at the end of life, new chapters have been added on the use of cannabis, nonpharmacological pain management interventions, wound care, care of the dying patient, and postmortem care. Each section of the second edition of this book focuses on nursing care at the end of life and offers concise, yet thorough, coverage of important topics. Throughout the book, numerous resources are provided and ‘Fast Facts’ boxes are used to highlight important pieces of information. Treatment options are also included in tables and figures throughout the book. Screening tools for depression, anxiety, and risk for wounds are included as well as scales that are important in hospice care, such as the Palliative Performance Scale and the Karnofsky Performance Scale.

As incredible it is to us to consider how far the ketogenic diet has come in 100 years, it is equally amazing to realize that this Ketogenic Diets book is now in its seventh edition, 25 years after its first publication by Demos Health. This edition continues the recent tradition of updating us every five years on what’s new and noteworthy in the use of ketogenic diets, and the authors appreciate many comments from parents and patients that this book has become a “gold standard” guide. The author’s intention is to continue to make this book helpful for everyone on the ketogenic journey: parents, patients, caregivers for sure, but also physicians, dietitians, scientists, nurses, and social workers. They consider it a success if it helped make ketogenic diet therapies more approachable and effective for you, your family, and/or your ketogenic diet center. Now, with over 10 years of experience, this seventh edition includes all-new material and guidance for adults starting dietary therapies, including information from a recent international expert guideline publication. For children, the 2009 pediatric ketogenic diet consensus statement was recently revised in 2018; details and changes from this important paper will be seen throughout this book. New chapters include exogenous ketones, a fifth ketogenic diet entitled the “modified ketogenic diet”, intermittent fasting, the influence of ketogenic diets on the gut microbiome, and expanded use for infants. Much of the final editing of this edition occurred during the COVID-19 pandemic, and the authors included information learned about how to manage ketogenic diet therapies in a crisis/pandemic situation. Finally, as ketogenic diets continue to be used by more countries every year, this book highlights some of the international recipes, cultures, and even scientific initiatives of this worldwide expansion.

Clinical trials are the engine of progress in the development of new drugs, procedures, and devices for the detection, monitoring, prevention, and treatment of cancer. A well-conceived, carefully designed, and efficiently conducted clinical trial can produce results that change clinical practice, deliver new oncology drugs, interventions, and diagnostics to the marketplace, and expand our understanding of cancer biology. This book presents the latest designs and methods of conducting and analyzing cancer clinical trials in the era of precision medicine with biologic agents including trials investigating the safety and efficacy of targeted therapies, immunotherapies, and combination therapies as well as novel radiation therapy modalities. It provides examples of real-life flaws and real-world examples for how to successfully design, conduct and analyze quality clinical trials and interpret them. With chapters written by oncologists, researchers, biostatisticians, clinical research administrators, and industry and FDA representatives. The book provides a comprehensive guide in the design, conduct, monitoring, analysis, and reporting of clinical trials in oncology. It covers various topics such as immunotherapy trials, radiation therapy trials, multi-arm trials, meta-analysis and adaptive design, use of genomics, dose modifications and use of ancillary treatments in investigational studies, establishing surrogate endpoints, practical issues with correlative studies, cost-effectiveness analysis and more. The book is organized into six parts containing 49 chapters. The first part provides background and introduction to oncology clinical trials which includes ethical principles guiding clinical research. The next two parts discusses designing and conducting oncology clinical trials such as phase I, II and III trials; confirmatory clinical trials, noninferiority trials, and quality of life studies. The fourth part describes analyzing results of oncology clinical trials. The fifth part talks about special considerations in oncology clinical trials. The final part discusses about cooperative groups, regulatory, and governing bodies involved in oncology clinical trials.

Infusion therapy can be delivered safely and effectively in the home setting. Successful home care agencies provide knowledgeable and qualified home care nurses and have structures and processes in place to ensure quality patient care. As an invaluable resource, this book can provide the framework for an effective home infusion therapy program that ensures optimal outcomes and patient safety. The first part of the book addresses the foundations of home infusion therapy. It describes the author’s model for safe infusion therapy, which provides a framework for the subsequent chapters. This model predicts that positive outcomes, including the absence of infusion therapy-related complications, patient satisfaction, and health care provider satisfaction, are maximized when four aspects of care are addressed during the home care planning process and during the process of providing care. The part discusses the importance of patient education. The role that patients and caregivers play in home infusion therapy is what makes home care unique. The nurse’s skill in teaching patients is equally important to any infusion administration skills. The part also describes concepts in infection prevention, an important goal of infusion therapy in all health care settings. The second part of the book addresses access devices and methods, including peripheral catheters, the growing use of midline catheters, and central vascular access devices, as well as subcutaneous infusion and intrathecal catheters. The final part of the book includes a chapter on infusion methods and issues followed by infusion therapy-specific chapters. Each of these chapters follows a similar format based upon the author’s model.

Physical medicine and rehabilitation (PM&R) is the medical specialty that focuses on the diagnoses, evaluation, and management of persons of all ages with congenital or acquired physical and/or cognitive impairments, disabilities, and functional limitations. The specialty began in the late 1920s and was recognized by the American Medical Association in 1945. PM&R physicians, also known as physiatrists, have expertise and knowledge about the biomechanics of the human body and an extensive understanding and training on how mobility can impact quality of life. Physiatrists treat persons with a broad range of medical diagnoses related to illness, injury, or physical impairment using nonsurgical techniques. As experts in physical examination, physiatrist can design a unique treatment plan tailored to an individual’s physical impairments, goals, and needs. Treatment goals can include restoration of function, but may also be supportive, accommodative, or through adaptive means. The fourth edition of the Physical Medicine and Rehabilitation Pocketpedia outlines the common conditions that PM&R physicians come across in their current clinical practice. It is a collaboration of over 60 content expert chapter authors, and each submission was streamlined to create a concise yet thoughtful chapter for each topic. It includes several new chapters, including COVID-19 rehabilitation, transplant rehabilitation, caring for patients with disability, orthotics/adaptive equipment, and pelvic health, which demonstrates the breadth of expertise within the field of PM&R. To make the book easier to navigate, the authors have significantly expanded the coverage of musculoskeletal rehabilitation and divided it into topic-specific sections. The book serves as a convenient and succinct resource for ongoing education and clinical practice in this field.

This handbook is structured to provide comprehensive care for the gynecologic cancer patient. It is directed toward clinicians at all levels of training and the chapters are tiered in this fashion. It outlines the basic diagnosis, workup, staging, and treatment. The book recommends specific surgical and adjuvant therapies that reflect the most current standards of care. Finally, it summarizes the evidence-based medicine in support of recommended treatments. Thus, the medical student can have a dedicated overview, the resident can refer to directed patient-care protocols, and the fellow and practicing physician can support their clinical decisions with easily accessible literature. The updated third edition furthers the content to include the latest cancer-screening information, new surgical technology and platforms, novel cytotoxic chemotherapy, in addition to targeted and immunotherapy treatments, vaccination information, and the most current clinical trial outcomes. The ninth edition AJCC staging guidelines have also been incorporated, providing accurate instructions for staging to keep the reader at the forefront of medicine. With this additional information, the authors continue to provide a comprehensive and contemporary reference for clinical practice. This book again acknowledges the dedication it has taken from the physicians, support staff, and especially our patients, to design and participate in the trials that have advanced the knowledge of these difficult gynecologic cancers. The authors hope the information provided herein can continue to guide high-quality care and reflect the commitment to the subspecialty.

Revised and updated, this third edition continues its tradition of providing evidence-based approaches to the specific technical aspects of delivering radiation treatment. Easy to read and relevant to general practice, this popular pocket-sized manual leads radiation oncology trainees and clinicians through the basics of radiotherapy planning and delivery for all major malignancies in a step-by-step manner. Organized by body site or system, each chapter provides technical details and clinical updates to planning as a result of practice-changing paradigms as well as new and updated equipment and techniques. Specialized topics such as palliative radiotherapy and pediatric radiotherapy round out the final chapters. With over 40 new images in addition to detailed accounts of advances in the field, this highly anticipated third edition provides important updates while retaining the valued, practical features of the previous editions. Written by members of staff in the Department of Radiation Oncology at the Cleveland Clinic, this edition continues to be a valuable resource for training as well as a reliable quick reference for professionals in the field such as radiation therapists and technologists, radiation nurses, dosimetrists, physicists, and practicing physicians. It presents concise summaries including target definitions and dose constraints for planning all major disease sites, provides updated coverage of planning associated with stereotactic body radiation therapy for prostate, pancreas, and liver cancers, and includes over 190 full color images. It also outlines new practice standards for hypofractionated radiation therapy in breast and prostate cancers and explains specific technical aspects important for the appropriate clinical delivery of radiation treatment.

This second edition of Pocket Guide to Radiation Oncology provides an updated and rapid review of the existing standard of care and the most relevant literature. Like the first edition, this quick pocket-sized reference can be carried for a quick review instead of heavy textbooks often filled with esoteric topics and lengthy minutiae. The book has new chapters on the growing areas of oligometastatic disease, benign indications, and proton therapy. The book comprises 55 chapters organized by site-specific diseases: central nervous system neoplasms, head and neck cancers, thoracic cancers, breast cancer, gastrointestinal cancers, gynecologic cancers, genitourinary cancers, lymphoma, sarcoma, skin cancers, pediatric malignancies, metastatic disease, and benign indications. The chapters present must-know key points, including treatment options by stage, technical considerations, and important items for follow-up. Clinical pearls and tables covering treatment options, dose constraints, side effects, target delineations, and treatment planning complete each chapter. The chapters conclude with a list of selected, summarized studies relevant to the disease. The book takes an efficient and no-frills approach to fundamental topics in the field, making it the perfect reference for a quick review for the board exam or MOC and even serving as a handy reference during a case review at a tumor board. The book provides essential, quick reference appendices on radiation therapy symptom management, normal tissue tolerance constraints, and radiation therapy and new systemic agents.

Continuous EEG monitoring is an important tool for assessing brain functions and allows clinicians to identify malignant EEG patterns quickly and provide more effective care. This book presents the wide range of technical and clinical issues encountered in successful critical care EEG. It focuses on the challenges of EEG interpretation that are unique to EEG monitoring in the ICU. The book is organized into five parts containing forty chapters. The first part describes technical issues such as EEG acquisition equipment, electrodes and montages, networking, remote monitoring and data storage, and staffing an ICU monitoring unit. The second part presents various indications for continuous EEG monitoring such as status epilepticus, ischemic stroke, subarachnoid hemorrhage, intracranial hemorrhage, infectious and inflammatory conditions, traumatic brain injury, and cardiac arrest. The third part focuses on EEG Interpretation and presents an overview of standardized critical care EEG terminology. Part four describes treatment of generalized convulsive status epilepticus, non-convulsive status epilepticus in adults, and status epilepticus in the pediatric population. It also discusses alternative treatments for refractory status epilepticus, and prophylaxis of seizures in the ICU population. The final part presents neonatal ICU EEG guidelines, American Clinical Neurophysiology Society (ACNS) consensus statement for pediatrics and adults, billing and coding for ICU EEG monitoring, report generation and communication with the ICU team, multimodality monitoring, and future directions for EEG monitoring in the ICU.

Inherited metabolic epilepsies represent a diverse group of disorders of inborn errors of metabolism in which epilepsy is a clinically significant component. This book, organized into six parts containing 43 chapters, is based on a sequential exposition of general principles, basic science, clinical science, small molecule disorders, large molecule disorders, and conclusions. Part I describe recognition, scope, and implications of inherited metabolic epilepsies and provides an overview of metabolic disease. Part II covers principles and mechanisms of metabolic epilepsies, metabolic energetics, an approach to molecular pathways with emphasis on the ubiquitous mechanistic target of rapamycin (mTOR) pathway that governs cellular proliferation and has implications from central nervous system (CNS) development to degeneration, excitatory/inhibitory imbalance that is at the heart of epilepsy, chaperone proteins representing a novel approach to metabolism, and neurophysiologic studies aimed at measuring neurotransmission. Part III explores neuroimaging including spectroscopy, electroencephalography, neuropathology, genomic technology, and use of the ketogenic diet in metabolic epilepsies. Individual disorders are categorized with the small versus large molecule format, with special emphasis given to certain metabolic disorders to highlight their unique characteristics. Part IV describes small molecule diseases such as amino and organic acid disorders, urea cycle disorders, pyridoxamine 5´-phosphate oxidase (PNPO) deficiency, disorders of GABA metabolism, DEND syndrome, Lesch-Nyhan disease to name a few. Part V presents large molecule diseases such as congenital disorders of glycosylation, lysosomal storage diseases, peroxisomal diseases, and leukodystrophies. The conclusion part covers diagnostic and therapeutic approaches, genetic counseling, family resources, and an algorithmic clinical approach to inherited metabolic epilepsies. The book will educate physicians, particularly specialists and trainees in pediatric and adult neurology, neurodevelopmental disabilities, epilepsy, and genetics, while caring for patients with inherited metabolic epilepsies, as well as spur further research into basic mechanisms and clinical trials in this group of maladies.

This book was designed to be a high-speed review—a last-minute gut check before the exam day. The authors created this review, which is a quick summary of the key topics one’ll encounter on the exam, to supplement to their certification preparation studies. They encourages the readers to use it in conjunction with other study aids to ensure they are as prepared as possible for the exam. This book, written by certified critical care nurses, follows the American Association of Critical-Care Nurses’ (AACN®) most recent exam content outline, and uses a succinct, bulleted format to highlight what one need to know. It will help the readers solidify their retention of information in the month or so leading up to their exam. Special features appear throughout the book to call out important information, including: complications: Problems that can arise with certain disease states or procedures; pearls: Additional patient care insights and strategies for knowledge retention; Alerts: Need-to-know details on how to handle emergency situations; pop quizzes: Critical-thinking questions to test your ability to synthesize what you learned; medication tables: Handy tables at the end of each body system chapter highlighting the indications, mechanisms of action, contraindications, and adverse effects of commonly administered medications; and list of abbreviations: A useful appendix to help guide you through the alphabet soup of clinical terms. We know life is busy. Being able to prepare for our exam efficiently and effectively is paramount, which is why the authors created this book. One have come to the right place as they continue on their path of professional growth and development. The stakes are high, and the authors want to help us succeed.

Designed as a last-minute gut check for the certification exam, this guide, written by medical-surgical nurses, provides quick, digestible nuggets of the most pertinent topics they encounter on the Medical-Surgical Nursing Certification Board (MSNCB) and American Nurses Credentialing Center (ANCC) exams. It can be used in conjunction with other study aids to ensure nurses are as prepared as possible for the exam. The certification helps to ensure quality patient care, indicates expert knowledge in the area of practice, and builds trust on the part of the patient and facility. It also establishes a high level of standards within healthcare, strengthens the nurse’s resume and job qualifications, and increases the potential for earning power. The book follows the most recent exam content outlines from the Certified Medical-Surgical Registered Nurse (CMSRN®) Certification Examination and the Medical-Surgical Nursing Board Certification Examination blueprints and uses a succinct, bulleted format to highlight what nurses need to know. It helps nurses solidify their retention of information in the month or so leading up to their exam. Special features appear throughout the book to call out important information including complications, nursing pearls, alerts, pop quizzes, and a list of abbreviations. The nursing pearls cover additional patient care insights and strategies for knowledge retention. The alerts include need-to-know details on how to handle emergency situations or when to transfer care. The pop quizzes cover critical-thinking questions to test nurses’ ability to synthesize what they have learned. Nurses encounter ethical dilemmas in caring for patients, including issues concerning access to care, informed consent, and treatment goals. Legal issues for nurses include both professional-centered and patient-centered concerns. The book deals with these professional and legal issues and the ways to address them. It serves as a quick refresher for registered nurses preparing for their certification examination.

This book was designed to be a high-speed review – a last-minute gut check before the Pediatric Nursing Certification Board (PNCB) and American Nurses Credentialing Center (ANCC) exam day. The authors created this review, which is a quick summary of the key topics one'll encounter on the exam, to supplement their certification preparation studies. They encourages the reader to use it in conjunction with other study aids to ensure the readers are as prepared as possible for the exam. This book follows the most recent exam content outlines from the PNCB and ANCC, and uses a succinct, bulleted format to highlight what one need to know. The aim of this book is to help the readers solidify their retention of information in the month or so leading up to their exam. It is written by certified pediatric nurses who are familiar with the exam and the content one need to know. Special features appear throughout the book to call out important information, including: Complications: Problems that can arise with certain disease states or procedures; Nursing Pearls: Additional patient care insights and strategies for knowledge retention; Alerts: Need-to-know details on how to handle emergency situations or when to transfer care; Pop Quizzes: Critical-thinking questions to test one’s ability to synthesize what one learned; and List of Abbreviations: A useful appendix to help guide you through the alphabet soup of clinical terms.

This book serves as a clinical guide to assist clinicians in prescribing psychotropic medications to address mental health conditions. It is used to assist clinicians to understand the key aspects of psychopharmacology. This is the first practical guide for novice and experienced nurse practitioners for explaining and choosing appropriate psychiatric medications. This clinical reference is ideal for students and all clinically oriented healthcare professionals since it provides concise, bulleted-style text for easy access to pertinent information. The book offers readers a broad understanding of the key aspects of psychotropic medications used in general psychiatry and primary-care settings and includes strategies to ease medication decision-making and evidence-based best practices to select and manage psychotropic medications. It is organized into two parts. Part I begins with an overview of general pharmacological principles and a brief overview of neurotransmitters, and covers the rationale for medication use and the risks and benefits of the major classes of psychotropic medications. Part II includes medications across drug classes that are divided by age population and includes practice management strategies, safety considerations, drug interactions, identification of side effects and adverse reactions, basic laboratory test recommendations, treatment options, and self-management strategies. The book ends with important concepts for patient and/or caregiver education and advocacy. It is intended for clinical healthcare providers, including physicians, nurses, APRNs, and other healthcare clinicians who need a practice guide, test review, or clinical resource guide that is easy to access and use.

This book provides a basic reference for nurses caring for women and their families during the antepartum and postpartum periods. It encompasses evidence-based practice guidelines and clinical recommendations for routine antepartum assessment and nursing care, care of women with pre-existing conditions prior to pregnancy or complications of pregnancy, routine postpartum assessment and care, postpartum complications, and care of special populations. Chapters are organized systematically to include assessment and management guidelines, health promotion and teaching recommendations, routine laboratory and ultrasound tests, and holistic evidence-based nursing care practices. A separate section addresses special populations and outlines care components specific to these women and their families. They include culturally diverse families, women on each end of the age spectrum, women with fetuses or newborns diagnosed with adverse outcomes, women who have a history of being victimized, and those with deployed partners. While targeted to hospital-based nurses and new nurses in hospital orientation and their preceptors, it is also a helpful resource for nurses who practice in a great variety of related settings, as well as nurse midwifery students. Appendices include a skills checklist, a list of commonly used medications, abbreviations, and lab values.

Bone and soft tissue sarcomas are a heterogeneous collection of over 170 distinct clinical entities. The prevalence of next-generation sequencing has accelerated the molecular classification and discovery of several new sarcoma entities and led to treatment paradigms. Sarcoma clinicians are applying the tools of precision medicine to identify driver mutations and select novel medications or agents in clinical trial. The landscape of sarcoma diagnosis and management is rapidly evolving with the advent of new diagnostic tools, precision medicine, immunotherapy, and cell-based therapies. The book’s content is structured by the most common sarcoma histologic subtypes as well as by general concepts. As sarcoma diagnosis and management requires an experienced multidisciplinary team, the book also includes overview chapters from each of the medical disciplines involved in the care of sarcoma patients. Importantly, each author was chosen based on his or her expertise specific to the content of the chapter. Each histologic subtype chapter includes a case-based study in which the reader is able to follow the diagnostic and treatment thought processes as the author illustrates their management of a complex medical situation. These cases illustrate commonly encountered situations in busy sarcoma clinics and allow the reader to apply the skills learned from the preceding chapter in understanding the author’s diagnostic and therapeutic approach. Significantly, the exceptional and novel digital version of this handbook allows rapid access to chapters or information through keyword searches at any time by computer, tablet, or smartphone. The editors design this handbook to facilitate management of sarcoma patients in an era of rapidly evolving sarcoma diagnoses and novel therapeutic approaches.

This book is a study guide/self-evaluation tool to prepare for the ABPN exam and MOC exam in vascular neurology. It is representative of the areas tested on the exam, including the standard clinical and basic science of stroke and some of the esoterica that appear on the exam. The book serves as a study guide for any neurologist, internist, or family practitioner interested in expanding his or her knowledge in this important field. The practice exam question-and-answer format is an effective and engaging study method, as opposed to a didactic review or summary reader. It is useful also to identify areas of weakness that require further study. The book has over 600 questions divided across fifteen sections. The fifteen sections are as follows: Basic Science; Vascular and Brain Anatomy; Clinical Pathology; Pharmacology and Pharmacokinetics; Epidemiology, Genetics, Primary Prevention; Ischemic Disease of the Brain and Spinal Cord; Hemorrhagic Disease of the Brain and Spinal Cord; Neuro-Ophthalmology; Cardiovascular Disease; Hematology; Pediatric Cerebrovascular Disease; Neurovascular Imaging; Clinical Trials and Ethics; Recovery and Rehabilitation; and Case Studies in Cerebrovascular Disease. The questions include cytotoxic edema following cerebral ischemia, internal carotid artery; cavernous malformations; thiazide diuretics; fibromuscular dysplasia; transient global amnesia; spinal epidural hematomas; ischemic optic neuropathy; atrial fibrillation; Von Willebrand disease; Perinatal ischemic stroke; cerebral microbleeds; modified Rankin scale; botulinum toxin and so on. Explanatory answers with appropriate references are included to facilitate learning. Most of the references are relatively recent, but for certain topics, the classic references, such as Niels Lassen’s work on incomplete cerebral ischemia and Anthony Furlan’s classic description of retinal ischemia presenting as visual change in bright light have been included.

This book is a novel and valuable resource for both neurologists and generalists. It is intended for medical students, mid-level practitioners, residents, and fellows in neuromuscular medicine. Chapters of the book are divided into global presentations that should be familiar to neurologists and other healthcare providers. It provides guidance well beyond the spectrum of neuromuscular disorders. Signs, for instance, are examined from the perspective of both central and peripheral nervous system causes, with etiologies succinctly outlined for quick review by the provider. Clinical pearls are offered to refine both history-taking and examination skills. Key features of neuromuscular disorders that present with the symptoms and signs discussed earlier in each chapter are summarized in tables, at times with guidance on laboratory testing to help narrow the differential diagnosis. Finally, there are brief overviews of treatment and management. The book is divided into nine chapters. The first chapter is devoted to interpretation of diagnostic testing used in neuromuscular disorders. The next three chapters discuss acute generalized weakness, subacutely developing weakness, and chronically developing weakness. The fifth chapter presents the different ways that episodic weakness and exercise intolerance might manifest, as well as which findings on the physical, electro diagnostic, and other assessments can point to different etiologies. The sixth chapter discusses the symptoms and signs of ocular and bulbar muscle weakness in the context of disorders of the peripheral nervous system. The seventh chapter covers the presenting complaints and physical examination findings in patients with neuromuscular respiratory failure as well as diagnostic studies commonly used in the workup of such patients. The penultimate chapter concentrates on sensory loss and neuropathic pain. The final chapter addresses limb pain, a common complaint evaluated by neurologists.

Considering the various comments the authors received from a variety of readers of the past editions, it was clear that this text needed to keep the format and hold the place in the sports medicine review category of thorough, yet succinct, texts. This third edition has kept true to the sports medicine board examination content outline in order to cover all topics testable on the examination. Even the length of each chapter is designed according to how much that topic is weighted on the examination. The authors have also kept the easy-to-read outline format as well as the reference lists at the end of each chapter, which can be used for more in-depth study of the topics. The book is divided into three primary sections: General Topics; Health Promotion and Injury Prevention; and Diagnosis and Treatment of Sports Injuries and Conditions. The third section is divided into the following four subsections: Musculoskeletal Injuries and Conditions; Medical, Neurological, and Psychological Conditions; Special Populations; and Hot Topics in Sports Medicine. The authors have added a new chapter to the Hot Topics subsection on exercise as medicine to supplement existing chapters on sports ultrasound and regenerative medicine. For this third edition, they have added rationales with detailed explanations of why one answer is correct and the others are not. The book is meant to be used as a study guide for primary care sports medicine physicians (family medicine, emergency medicine, internal medicine, pediatrics, and physical medicine and rehabilitation) and orthopedic sports medicine physicians preparing to take the sports medicine subspecialty examination for initial certification or recertification. It also can serve as a sports medicine reference for other medical professionals such as athletic trainers, physical therapists, chiropractors, advanced practice providers, physicians in training (i.e., interns, residents, and fellows), and other physicians interested in sports medicine.

An understanding of biostatistics is necessary for reading and comprehending published literature, for performing retrospective research, and for designing and analyzing prospective clinical trials. Biostatistical concepts are also tested on oncology board exams. This book is organized into four sections covering 13 chapters. Section I begins with the basic foundations of biostatistics that are tested on board exams such as summarizing and graphing data, sampling, and statistical estimation. In Section II, these basics are then expanded on to include the concepts used in retrospective study design, analysis, and interpretation. It discusses hypothesis testing, correlation, regression, categorical data analysis, survival analysis methods, and noninferiority analysis. Section III focuses on prospective clinical trials, guiding readers in their understanding of published clinical trials and in the design and analysis of novel clinical trials. It describes cohort studies, case-control studies, cross-sectional studies, matched studies, analysis of studies, and sample size. The final section presents self-study multiple choice questions with answers and rationales.

Countless physicians, medical students, and therapists can describe a similar experience at one time or another during their training: a patient is behind the door in an examination room and the daily schedule has the words “shoulder pain” listed as the chief complaint. Depending on one’s experience or comfort level, many questions may immediately flood one’s mind regarding how to approach the patient: What are the various causes of shoulder pain? Is the pain really coming from the shoulder? What structures are important in the shoulder? What aspects of the physical examination will help distinguish one shoulder problem from another? The physical examination of musculoskeletal and peripheral nervous system problems is essential knowledge for broad areas of healthcare, as these problems are among the leading reasons for medical encounters. This pocket reference offers instant access to a wide array of clinical pearls to guide the physical examination and diagnosis. Whether one can choose to keep the print copy handy or use the digital version on our phone or tablet, our answer is quickly within reach. In this updated and refreshed second edition, one can search by body part or suspected diagnosis and find detailed descriptions of physical examination maneuvers, along with associated evidence of sensitivity and specificity, to help us with our diagnosis. Additionally, the reader will find all new colorized illustrations, high-resolution photos demonstrating the maneuvers, and corresponding videos that bring the examination to life. Video icons throughout chapters indicate which tests include an accompanying video. There is no substitute for excellent physical diagnosis skills. The authors hope that one will find this book useful as one develop and fine-tune their skills in order to give patients the very best care.

SITC’s Guide to Managing Immunotherapy Toxicity is a practical reference to managing side effects associated with FDA-approved cancer immunotherapy drugs. Part I contains chapter-based overviews of immune checkpoint inhibitors in the clinic, starting with Anti-CTLA-4 agents, Anti-PD-1/PD-L1 agents, and approved immunotherapeutic combinations. These chapters cover relevant mechanisms of action, indications, and toxicities seen while combating early, advanced, and metastatic stages in cancer patients. Part II is structured by common and uncommon toxicities that affect major organ sites throughout the body. It begins with a general summary of principles and management options followed by chapters focusing on specific toxicities such as rash and mucosal irritation, muscle and joint toxicity, diarrhea and colitis, pneumonitis, endocrine toxicities, neurological toxicities, cardiac toxicity, renal toxicity, hematologic toxicity, and ocular toxicities. Each chapter provides guidance on how to assess and treat the toxicity and how to support the patient through acute and chronic effects with detailed summary tables for quick reference. Part II concludes with chapters covering management of special patient populations, including patients with autoimmune disease and geriatric patients, treatment and management of fatigue, and a final chapter dedicated to cost effectiveness and the toll of ‘financial toxicity’ on patients and caregivers. With chapters written by world-recognized oncology leaders in the immuno-oncology field, this text provides thorough coverage of the toxicity and management of adverse effects for immune checkpoint inhibitors. It is an indispensable resource for clinical oncologists, emergency physicians, hospitalists, and other medical practitioners in both the hospital and community clinic settings, especially as the use of immune checkpoint inhibitors becomes a fixture in oncology care.

This book provides a practical and concise text for electromyography (EMG) rotations and is a great companion to the larger reference texts that successful electrodiagnosticians also need. It provides more of the practical information on EMGs that made the first edition so successful. In addition, it includes pictures, text, clinical pearls, questions, and tables and provided novel chapters such as the use of ultrasound in electrodiagnostics. These chapters are written by some of the foremost and experienced authorities in the field. This book includes 35 chapters. These chapters are organized into six sections. Section I consists of Chapters 1–3. It provides introduction to electrodiagnosis, instrumentation and systematic approach to learning and performing nerve conduction studies. Section II consists of Chapters 4–9. It discusses motor and sensory studies of upper limb and lower limb. Section II also discusses the F-waves and H-reflexes. Section III consists of Chapters 10–13. It provides basic approach to EMG technique and waveform recognition. Section III also describes motor unit action potential analysis and recruitment. Section IV consists of Chapters 14–17. It discusses orthodromic and antidromic nerve conduction studies; temporal dispersion and phase cancellation; interpreting studies; and common anomalies. Section V consists of Chapters 18–33. It discusses carpal tunnel syndrome; neuropathy of ulnar and radial; anterior interosseous nerve lesion; fibular and tibial neuropathy; lumbosacral and cervical radiculopathy; facial nerve and blink studies; repetitive stimulation and neuromuscular junction disorders; peripheral neuropathy; brachial plexopathy; motor neuron disease; myopathy; and the use of ultrasound with electrodiagnosis. Section VI includes Chapters 34 and 35 which include study checklists and the answers to the multiple choice questions located within the chapters.

Women have unique biopsychosocial factors that make them more vulnerable to mental illness. Many of these mental illnesses can elicit enormous physical, emotional, financial, and social barriers. This is books serves as a quick-access clinical guide to the range of mental health issues and diagnoses that commonly affect women across the life span. The book is divided into four sections. The first section deals with the role of cultural competence in mental health and the various types of violence such as sexual assault, rape and stalking perpetrated on women. It emphasizes key stressors specific to women that are precursors to mental illness. The second section looks at the mental disorders affecting special populations among women including girl children and adolescent females, and aged women. Disorders for other unique populations such as disabled women, lesbian and transgendered women, female veterans, women with forensic health concerns, and women who have been the object of violence are also discussed here. In the third section, chapters address childbearing issues, including menstruation-related problems, infertility and its psychological implications, and antepartum, intrapartum, and postpartum psychological disorders. The final section of the book is devoted to the discussion of the various psychiatric issues common to women: anxiety disorders; mood disorders; eating disorders; personality disorders; psychotic disorders; sleep disorders; substance abuse disorders; grief and loss; schizophrenia; and sexual dysfunction.

This book is a comprehensive guide for the practicing physician and medical physicist in the management of complex intracranial and extracranial disease. It presents the scientific principles, clinical background and procedures, treatment planning, and treatment delivery of stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) for the treatment of tumors throughout the body. The book is organized into two parts comprising twenty chapters. Beginning with an overview of SRS and SBRT, Part one provides insightful coverage on topics such as the evolving radiobiological principles of radiosurgery and SBRT, SRS and SBRT process, patient immobilization, imaging, treatment planning process, and technologies and equipment used for SRS and SBRT. It also contains focused chapters on quality assurance, quality management, and patient safety. Part Two describes the clinical application of SRS and SBRT for tumors throughout the body. The body regions covered includes brain, head and neck, lung, pancreas, adrenal glands, liver, prostate, cervix, and spine. It also has a chapter on oligometastatic disease. Each clinical chapter includes an introduction to the disease site, followed by a thorough review of all indications and exclusion criteria, in addition to the important considerations for patient selection, treatment planning and delivery, and outcome evaluation. These chapters conclude with a detailed and site-specific dose constraints table for critical structures and their suggested dose limits. The final chapter discusses immunoradiosurgery. The book is enhanced with supplemental video tutorials and is a must-have book for clinicians, physicists, and other radiation therapy practitioners.

The years that encompass the period of adolescence are largely socially constructed and dependent upon the norms, beliefs, and behaviors of society. Adults interacting with teens, whether in their personal or professional lives, know the rewards, challenges, and sometimes the mysteries of these experiences. This book is designed to assist nursing and health care professionals to understand and to be successful in these interactions, to have positive impacts on teens, and to advocate effectively for youth. Teen development is an ongoing process of engagement with friends, adults, and institutions, and teens’ own perspectives that frame their individual responses, thoughts, and actions. Knowledge of brain development helps us to understand some aspects of teen behavior characteristic of early, middle, and late adolescence. Adolescent development, factors affecting teen health, suggestions for working and communicating with teens, and issues impacting adolescents in six holistic health domains, namely physical, intellectual, emotional, spiritual, sexual, and relational are addressed in the book. Selected issues facing teens with acute and chronic illness, matters associated with teens and technology, legal and ethical issues, and the marginalization of youth challenge readers to ponder their perceptions about adolescents.

Androgen deprivation therapy (ADT, often called hormone therapy) is a common treatment for prostate cancer, but it has a wide range of side effects. This book presents techniques to minimize the burden from those side effects. Most physicians who prescribe ADT warn patients about the most serious effects, but do not have the time to discuss all of the side effects that a patient might experience. This book will help to fill in what may not get covered in the clinic when a physician tells a patient, “I recommend that you start on hormone therapy”. It is structured as a workbook, which means that it includes not just information but also exercises. The book covers not only the physical side effects of ADT but the psychological side effects that can alter how one feels and how one interacts with loved ones. Importantly, it recognizes that ADT impacts not just patients, but also their partners and others close to them. Some sections are appropriate for all loved ones; others are specifically for sexual partners. For the book to be most effective for couples, both patients and partners need to read the book and to explore together the questions and exercises at the end of each chapter. Questions at the end of each section are designed to help one think about how this information applies and facilitates communication with one’s loved ones. Some questions specifically address couples; others are appropriate for individuals, or for patients who are dating or hope to date in the future. A major change in this edition is the expansion of discussion on the drugs used for ADT and how they are used in combinations with other medications. This testifies to the many advances in treating patients on ADT that have improved since we first began studying ADT.

The book begins with a brief overview of the various types of genetic alterations that are encountered in cancer, followed by accessible and applicable information on next generation sequencing technology and bioinformatics, tumor heterogeneity, whole genome, exome and transcriptome sequencing, epigenomics, and data analysis and interpretation. It provides essential explanations of concepts, terminology, and methods. The book includes tips for interpreting and analyzing molecular data, as well as a discussion of molecular predictors for targeted therapies covering hematologic malignancies and solid tumors. It explains the use of FDA-approved genomic-based targeted therapies for breast cancer, lung cancer, sarcomas, gastrointestinal cancers, urologic cancers, head and neck cancer, thyroid cancer, and many more. The book provides essential understanding of the molecular and genetic basis of cancer and the clinical aspects that have led to advancements in diagnosis and treatment. It describes how cancer genomics and next generation sequencing informs cancer screening, risk factors, therapeutic options, and clinical management across cancer types. The book explains what mutations are, what tests are needed, and how to interpret the results and provides information on FDA-approved targeted therapies that are being used in the clinic. Finally, it covers different sequencing platforms and technologies and how they perform in research settings.

This atlas serves as a comprehensive working reference for a wide range of clinicians practicing in the field of clinical neurophysiology (CNP). It highlights the traps and pitfalls associated with artifact when interpreting studies involving CNP. Various forms of neurophysiological procedures are performed routinely at local CNP laboratories throughout the world. They are interpreted by neurologists and neurophysiologists including studies involving electroencephalography (EEG); electromyography (EMG); and nerve conductions studies (NCS), sleep, autonomic neurophysiology, evoked potentials (EP); and magnetoencephalography (MEG). It illustrates common and rare types of artifacts that may be encountered by the clinical practitioner during the course of performing CNP studies. The book provides an explanatory text with samples of artifact that emphasize essential principals existing within individual fields of CNP. It is developed in atlas form to facilitate easy interpretation for the busy clinician practitioner. The book comprises of 14 chapters. Chapter one provides an overview of CNP. Chapter two focuses on an explanation of analog recording concepts and provides explanation of important digital recording concepts. Chapter three illustrates the impact of artifact in pediatric studies involving the peripheral nervous system. Chapter four describes artifacts of neuromonitoring. Chapter five addresses continuous EEG monitoring in ICU patients. Next two chapters discuss artifacts in pediatric and adult electroencephalography. Chapter eight addresses pediatric and adult magnetoencephalography. Chapter nine reviews the difficulties encountered with artifact involved when performing EMG and NCS. Chapters ten through thirteen address artifacts in autonomic neurophysiology studies, polysomnography, evoked potential recordings, and neurophysiologic intraoperative monitoring. The final chapter discusses the most common techniques for artifact reduction.

A noticeable evolution of the nature of the literature and education in recent years is that the emphasis has changed from simply attempting to demonstrate that peripheral nerve sonography has value, to more intricate nuances of medical precision. With the progression of understanding, improvements have been made with peripheral nerves in terms of identification of normal anatomy of even very small nerves, diagnostic acumen in pathologic conditions, safety and efficacy of anesthetic blocks, and even improved visualization and innovation for ultrasound-guided therapeutic procedures. The importance of combining anatomic information with physiologic testing for neuromuscular disorders has become increasingly more evident and ultrasound has found its way into electrodiagnostic laboratories throughout the world. As a result, there is now widespread production of combined instrumentation with capabilities of both electrophysiologic testing and sonographic imaging. It can be argued that what was once termed electromyography and nerve conduction testing should now be considered electromyography, nerve conduction studies and ultrasound. This book adds new chapters on the evaluation of muscle and ultrasound-guided peripheral nerve procedures. Many of the existing chapters have significant additions of imaging of more challenging nerves and smaller nerve segments, which are new to this edition. The addition of ultra-high frequency sonography allows unprecedented visualization of peripheral nerves. Most of the original images in the book were replaced, and the addition of so many new normal peripheral nerve images has led to the addition of “Peripheral Nerves” to the book title. There are also over 420 videos presented for instruction in dynamic visualization. Additionally, all of the case presentations that demonstrate the clinical approach of various focal neuropathies through the use of ultrasound are new to this text.

This book contains over 800 questions with answers and detailed explanations covering all areas of the complex subspecialty of clinical neurophysiology. It is divided into eight chapters covering anatomy and physiology, electronics and instrumentation, nerve conduction studies and electromyography, electroencephalography (EEG), evoked potentials and intraoperative monitoring, sleep studies, ethics and safety, and advanced topics including quantitative EEG, magnetoencephalography, transcranial electrical stimulation, autonomic testing, and more. Liberal use of image-based questions illustrating the full spectrum of neurophysiologic tests and findings build interpretive skills. Questions are randomized and include both case-related questions in series and stand-alone items to familiarize candidates with the question types and formats they will find on the exam. This book is recommended for its intended audience and candidates for board certification in a field of clinical neurophysiology. It can be a useful resource for fellows during their training. The book is in a Q&A format with answers and detailed rationales to facilitate recall of must-know information and help identify knowledge gaps for further study. The book provides case-based questions in series to simulate full range of board question types. It includes numerous state-of-the-art digital images to ensure familiarity with studies and findings that form a significant part of any certifying exam and contains a unique Pearls for Passing chapter, Chapter 9, for quick review of key facts.

Physical medicine and rehabilitation (PM&R) is one of the broadest and most challenging specialties in medicine. Physiatrists see patients of all age groups with impairments of every organ system and must have a keen understanding of anatomy, biomechanics, ergonomics, exercise physiology, kinesiology, neurophysiology, pharmacology, and psychology. They not only prescribe medications and perform procedures, but also prescribe prosthetics, orthotics, splints, and complex medical equipment. They lead interdisciplinary teams that address the holistic bio-psycho-social and spiritual needs of people with disabling conditions. In PM&R, board certification has three components: The first component, Part I, is a written examination testing medical knowledge; the second component, Part II, is an oral examination that tests clinical practice skills. The third component, Part III, is maintenance of certification. The Accreditation Committee for Graduate Medical Education defined six core competencies for physicians: medical knowledge, clinical care, practice-based learning, communication, professionalism, and systems-based practice. Part I tests the first of these competencies, while Part II tests the remainder. This workbook is an additional tool, unique in its format. It walks the reader through cases in an interactive format. The cases are structured in a similar format to The American Board of Physical Medicine and Rehabilitation (ABPMR) Part II. The content mirrors the exam outline, which is available on the ABPMR website. The exam consists of questions about case vignettes. Each vignette fits into one or more diagnostic categories, and each may focus on one or more evaluation or management skills. Each case tests five clinical skills: data acquisition, problem-solving, patient management, system-based practice, and interpersonal and communication skills. While the text is intended as a board review workbook to be used in preparation for the Part II exam, other audiences will find it helpful as well.

This fifth edition offers a comprehensive, user friendly, clinically focused resource for busy clinicians, advanced practice students, and faculty. Previous editions focused on the assessment of women and related women’s health skills and procedures. This book continues to provide updated skills and procedures, along with enhanced tables and figures, to help clearly describe these basic and advanced skills. Responding to reader requests, chapters now include (if appropriate) management/pharmacology summary charts and case studies. The book expanded into management of various women’s health conditions, the need to include additional topics became apparent. This led to fourteen new chapters written by content experts. These chapters include telehealth in women’s health; vaginal infections and vaginal microscopy; mental health screening; preconception care; complementary and alternative medical therapies; adolescent health; lactation assessment and management; female veterans; male sexual and reproductive health; amenorrhea; premenstrual syndrome/premenstrual dysphoric disorder; sexual health and related problems; human trafficking; and the contraceptive consult. All chapters have been updated and expanded to reflect current research, evidence-based clinical guidelines, and new technologies. The book begins with a comprehensive review of the basic anatomy and physiology of women/persons with a vagina. A complete under-standing of the complexities of the menstrual cycle and normal vaginal flora, examined at the cellular level, is imperative for accurate understanding and diagnoses of conditions that affect this community. The book offers practical guidance to help advanced practice students, preceptors, faculty, and clinicians. The content reflects an extensive review of current literature integrated with our authors’ extensive years of clinical experience and teaching. In addition, it welcomes expanded panel of advanced practice clinicians from a wide variety of women’s health specialties who have generously shared their expertise as contributing authors and reviewers.

Cancer affects 1.7 million new lives each year. Over 60" of those diagnosed with cancer will undergo radiation therapy at some point in their disease process–whether for curative intent or for palliation. Radiation oncologists take great care to accurately target tumor and minimize normal tissue irradiation. This book provides a concise summary of the presentation and management of both acute and late radiation side effects. The ability to effectively manage the acute effects on patients undergoing treatment is critical for radiation oncology professionals as well as other medical fields, as patients are treated in multidisciplinary fashion. Most late-appearing effects from radiation are uncommon. The book is a collection of the experience of disease site experts who see and treat both acute and late effects with frequency. Their summarized evidence-based practice provides guidance to anyone whose practice touches cancer patients and survivors. The book is a useful and practical guide in practice, whether it be daily management or as reference for the occasional patient with a history of radiation. The book is divided into thirteen chapters. The first chapter addresses radiation therapy effects on the central nervous system. The second chapter presents radiation therapy effects in head and neck cancer. The third chapter describes radiation therapy effects on the thorax. The fourth chapter analyzes radiation therapy effects in breast cancer. The next three chapters presents radiation therapy effects on the abdomen, pelvis, and on skin and extremities. Chapter 8 reviews radiation toxicity management in children. The ninth chapter discusses the systemic effects of radiation therapy. The tenth chapter analyzes radioprotection for radiation therapy. Chapter 11 discusses the risk and prevention of radiation-induced cancers. Chapter twelve describes the approaches and challenges in cancer survivorship. The final chapter talks about maximizing the health and wellness of cancer survivors through healthy lifestyle behaviors.

The concept behind the creation of this first edition of the Handbook of Pediatric Rehabilitation Medicine stemmed from the consideration of the need to provide information about key concepts in pediatric rehabilitation more effectively to students, residents, and fellows on pediatric rehabilitation rotations. As the subspecialty of pediatric rehabilitation medicine has grown in scope, so has the need to expand the knowledge base not only within the subspecialty, but also to other subspecialties and clinicians who many times are caring for the same children that we are. This book has been created with this focused, yet broader call to convey key clinical information to all clinicians who provide care to children with complex medical and rehabilitation needs. It provides easily accessible key information that is portable. The latest information has been organized efficiently in each chapter through the combined use of text and bullet points to allow for rapid access in clinics and inpatient units, or to refer to while studying for boards. The chapters are grouped for easy reference into growth and development, central nervous system disorders, neuromuscular disorders, musculoskeletal, general, and miscellaneous sections. The book is intended for medical students; trainees in rehabilitation medicine, neurology, orthopedics, and pediatrics; practicing pediatricians, pediatric subspecialists, and primary care physicians; allied health professionals, including physical, occupational, and speech therapists; and advanced practice providers and nurse practitioners.

The use of high frequency ultrasound as an imaging modality for the musculoskeletal system has expanded dramatically in the past decade. Despite its growth, standardized training for use of this modality is not yet available in the majority of residency training programs. This book illustrates and teaches the basic components of many of the skills and knowledge needed to begin incorporating the use of ultrasound in a musculoskeletal practice. The goal is provide a simplified approach for those getting started in musculoskeletal ultrasound. This includes developing understanding in use of the controls and function of the ultrasound machine, commonly used terminology, obtaining and optimizing the image, and proper scanning technique and the ergonomics involved. The book is also designed to instruct in the recognition of the appearance of various musculoskeletal tissue, commonly seen artifacts, foreign bodies and masses, and understanding basics of interventional ultrasound. It also provides an understanding of the basic physics used in ultrasound. Principles of further advancement of skills and initiating a practice are discussed. Doppler imaging helps to identify certain vascular structures, gives an indication of vascular flow, and can also be used to assess for increased vascularity in pathologic conditions. Separate chapters cover imaging of tendons, muscles, and nerves. Ultrasound allows visualization of both the needle and soft tissue target in real time. This improves accuracy of needle placement for both injection and aspiration procedures.

This book is the first resource fully dedicated to quantitative EEG (QEEG) analysis, tailored for physicians or EEG technologists who work with critically ill patients. With the rise of continuous EEG monitoring in intensive care, clinicians are increasingly called on to make real-time clinical judgments with little formal guidance on how to interpret QEEG. The book is configured to meet daily practice challenges. It addresses not only technical fundamentals, but also provides numerous examples of signature QEEG patterns and artifacts to instruct both untrained and experienced eyes. The book walks the reader from essential principles all the way through to practical pattern recognition. With full-page reference samples pairing raw EEG with quantitative EEG spectrograms, brief clinical vignettes, and explanatory captions noting significant features, it provides a roadmap for understanding and applying QEEG data in critically ill patients. The book contains more than 400 full-page vivid color QEEG examples paired with raw EEG to build interpretive skills and enhance clinical decision-making. It presents thorough discussions of both normal and abnormal findings and QEEG artifacts that set the standard for effective use of quantitative electroencephalography and trend analysis in the ICU. The book is organized into three sections. Section one presents the principles of quantitative electroencephalography. Section two discusses the clinical practice of quantitative electroencephalography. Section three describes the artifacts in quantitative electroencephalography. Complete with a broad range of patterns and page after page of full-color samples, the book is designed to be the authoritative QEEG reference for neurologists, intensivists, technologists, and trainees working in critical care settings.

This book establishes a standard in practice, education, and training with the introduction of a coordinated competency-based approach to shape the future of physiatric patient care. It is divided into two parts. In Part I, foundations for the core competencies are provided with some basic principles for application toward competency-centric practice entwined with professional education strategies. Part II focuses on the major physiatric areas of practice with information specific to each area organized in the context of the six Accreditation Council of Graduate Medical Education (ACGME)/American Board of Medical Specialties (ABMS) core competencies and quality metrics. Each practice chapter includes goals and objectives for the six competencies, a case study with open-ended discussion questions, and self-examination questions and answers for self-assessment. The physiatric areas of practice covered in the second part include extremity limb loss and amputation, cardiopulmonary and cancer rehabilitation, stroke, traumatic brain injuries, spinal cord injury, Parkinson’s disease and multiple sclerosis, neuromuscular and musculoskeletal diseases, osteoarthritis and rheumatoid arthritis, and lumbar spine disorders. In addition, pediatric traumatic brain injury and juvenile idiopathic arthritis are also discussed. The book can be used independently to build essential skills for patient-centered care or as part of a physical medicine and rehabilitation resident training curriculum as a useful adjunct during clinical rotations.

This book is designed to assist and guide healthcare professionals in prescribing home exercise programs in an efficient and easy to follow format. With patient handouts that are comprehensive and customizable, this manual is intended for the busy practitioner in any medical specialty who prescribes exercise for musculoskeletal injuries and conditions.

The most central aspect of any therapeutic exercise program is the patient’s ability to perform the exercises effectively and routinely at home. This book is organized by major body regions from neck to foot and covers the breadth of home exercises for problems in each area based on the current literature. Each chapter begins with a brief introduction to the rehabilitation issues surrounding the types of injuries that can occur and general exercise objectives with desired outcomes, followed by a concise review of the specific conditions and a list of recommended exercises. The remainder of the chapter is a visual presentation of the exercises with high-quality photographs and step-by-step instructions for performing them accurately. The most fundamental exercises to the rehabilitation of each specific region are presented first as the essential building blocks, followed then by condition-specific exercises that advance throughout the chapter. Using this section, the healthcare practitioner can provide patients with handouts that require little to no explanation and can customize the program and modify instructions to fit individual patient needs and abilities—with confidence the handouts will be a valuable tool to help patients recover successfully from musculoskeletal and sports injuries.

From its initial ophthalmologic indications, the number of approved, accepted, and proposed uses for botulinum neurotoxin (BoNT) therapy has expanded to include a large number of applications for various body systems. At the same time, developments in the field of ultrasound (US) including high frequency linear transducers technology have led to the rapid expansion of US for both diagnostic imaging and procedural guidance. Physicians who perform chemodenervation procedures have long recognized the limitations of standard techniques used to localize muscles or nerves. This has led an increasing numbers of physicians to explore and promote US imaging as a practical and more accurate alternative guidance technique for these procedures. Although there numerous texts and atlases specific to the subject of musculoskeletal ultrasound and for the subject of neurotoxin therapy/chemodenervation, there is limited reference material for physicians on ultrasound guidance for chemodenervation including neurotoxin therapy. The purpose of this Atlas is to provide a review of neurotoxin therapy with a strong emphasis on ultrasound technology and its applications for chemodenervation. The authors hope the material presented in this text/DVD will reduce at least one barrier that physicians encounter when trying to add US-guided chemodenervation procedures in the clinic. The text section of the book provides an introduction or review of US technology, scanning techniques and image optimization required for US-guided neurotoxin/chemodenervation. The illustrated print and DVD Atlas sections serve as a reference manual for physicians to be used during US-guided chemodenervation procedures. The authors hope the material provided in this multimedia text will serve to educate clinicians, expand their knowledge of US and chemodenervation focused on BoNT therapy and reduce the risks inherent in these procedures and enhance patient care.

This book provides an up-to-date practical clinical guide to evidence-based stroke recovery and rehabilitation built on a foundation of basic neurophysiology, neuroscience, and psychological science. It provides in-depth information on the assessment and management of all acute and long-term stroke-related impairments and complications including cognitive dysfunctions, musculoskeletal pain, and psychological issues. The book examines risk factors, epidemiology, prevention, and neurophysiology as well as complementary and alternative therapies, functional assessments, care systems, ethical issues, and community and psychosocial reintegration. It features expanded coverage of key issues such as the role of robotics and virtual reality in rehabilitation. Chapters have been incorporated to cover fields of recent exploration including transcranial magnetic stimulation, biomarkers, and genetics of recovery as well as essentials like the use of medication and the survivor’s perspective. The up-to-date presentation of scientific underpinnings and multi-specialty clinical perspectives from physical medicine and rehabilitation, neurology, physical therapy, occupational therapy, speech and language pathology, and nursing ensures that the book will continue to serve as an invaluable reference for every health care professional working to restore function and help stroke survivors achieve their maximum potential.

Ambulatory electroencephalography (aEEG) monitoring is not limited to the home environment. It is a useful diagnostic test to evaluate an individual in whom seizures or seizure-like episodes are suspected in their natural environment wherever that may be. This book reviews some of the background distinctions for the technique of aEEG and instrumentation and polygraphic aEEG recording. aEEG monitoring often yields information in the evaluation of epilepsy and in the differential diagnosis of other conditions that mimic epilepsy including psychogenic nonepileptic seizures (PNES), syncope, cardiogenic etiologies, parasomnias, migraine, and transient ischemic attacks. The book discusses the yield of aEEG and compares it with other short- and long-term monitoring techniques in epilepsy. It then provides a thorough assessment of ambulatory sleep studies. Chronic intracranial aEEG monitoring is covered with a new type of aEEG monitoring to provide not only electrocorticography but also encompass treatment using neuromodulation. The book also delivers an inside look at aEEG in the future with development of “wearables” that will allow us to learn new information that involves not only detection but prediction. The practical implications of aEEG involved in proper coding and billing are also reviewed. Case histories are included of patients evaluated with aEEG to underscore key points of practical value.

Modern-day research has tapped into a deeper and more complex understanding of cytokine- and cell-based regeneration theory that translates well into the clinical paradigm of regenerative medicine. Regenerative medicine is fundamentally a modern-day method of enhancing the human capabilities of healing. Today’s standard treatment options in orthopedics and sports medicine are being replaced by regenerative medicine interventions. This book presents nonsurgical treatment options offering a new paradigm that enhances the natural healing of injuries and degenerative pathologies such as meniscal and rotator cuff tears. It is intended as a working reference for practitioners, offering a concise, evidence-based rationale for regenerative medicine in the world of sports medicine. The book is divided into fourteen chapters. The first chapter focuses on current concepts in the pathophysiology of orthopedic conditions affecting treatment. The second chapter introduces the reader to common terminology used in regenerative medicine. The third chapter deals with regulatory issues regarding the clinical use of regenerative treatments. Chapter 4 discusses the clinical and administrative considerations in performing regenerative procedures. Chapter 5 explores regenerative medicine in the canine. Chapters 6 and 7 present the principles of Platelet-Rich Plasma (PRP) and stem cells, and scientific evidence of PRP for orthopedic conditions. Chapter 8 reviews the application of PRP to enhance the outcomes of various orthopedic surgical procedures. Chapter 9 review several emerging areas in regenerative medicine for orthopedic conditions: amniotic and umbilical cord products, interleukin-1 receptor antagonist protein, and alpha-2 macro-globulin. Chapter 10 describes the setup and procedures for performing PRP injections. Chapter 11 presents the basic science and rationale for using stem cells for orthopedic conditions. Chapters 12 and 13 describe harvesting techniques of bone marrow and adipose for stem cell procedures, and techniques for performing regenerative procedures for orthopedic conditions. The final chapter presents physical therapy considerations following regenerative medicine interventions.

Courses in epilepsy and EEG education are available through several national and international societies. However, there are few textbooks available for those interested in obtaining a well-rounded education in this discipline. This book contains enough information to provide an excellent foundation for understanding epilepsy and is concise enough to be read cover-to-cover. For easy readability, the book is divided into four parts. Part I covers the clinical aspects such as pathophysiology, genetics, epidemiology, etiology and differential diagnosis as well as epileptic seizures, epilepsy syndromes and neonatal seizures. The second part is devoted to various diagnostic procedures in a variety of settings. These include normal EEG, ambulatory EEG, EEG in an ICU, seizure semiology, scalp video and intracranial EEG, brain mapping, structural and functional neuroimaging, the Wada test, and epilepsy surgery and neuropsychological evaluation. Treatment aspects are dealt with in Part III. Chapters cover the first-, second- and third-generation antiepileptic drugs (AEDs) as well as the newest antiepileptic drugs and drugs in development. Epilepsy surgery and stimulation and dietary therapies are also examined. A separate chapter looks at alternative therapies including mindfulness meditation, yoga, Reiki and healing touch. The last part on special situations includes chapters on metabolic epilepsies, bone health, headaches, and the sudden unexpected death in epilepsy (SUDEP).

Cancer patients frequently present with scenarios for which level I evidence is not available and a more individualized approach to each patient is warranted. This book analyzes common difficult clinical situations from various vantage points. It presents case examples which were developed to guide discussions on treatment recommendations, with a review of current issues, and any potential data utilized to drive treatment decisions. The cases are organized into sections corresponding to the major treatment areas of radiation oncology: Breast, Gastrointestinal, Gynecology, Genitourinary, Head and Neck, Thorax, and Central Nervous System. Radiation oncological apsects are discussed for several difficult cases of breast cancer, pancreatic cancer, rectal cancer, anal cancer, endometrial cancer, prostate cancer, laryngeal carcinoma, oral tongue cancer, small-cell lung cancer, non-small cell lung cancer, anaplastic oligodendroglioma and glioblastoma. The book provides residents, fellows, and clinicians with a practical, evidence-based guide to the current management of difficult cases in radiation oncology. Emphasis is on the management of those clinical challenges commonly seen in practice that the community practitioner would normally handle without outside referral.

This book provides a comprehensive and concise visual reference on acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) seen in children and adults. It addresses all aspects of AML and ALL including their risk factors, cytogenetics and mutational characteristics, diagnoses, clinical management and prognoses which are imperative and challenging for medical students, residents, hematology and medical oncology fellows, and even community oncologists and hematologists. The book focuses on issues surrounding the epidemiology, diagnosis, treatment, and overall management in both pediatric and elderly patients; psychosexual issues that arise as a consequence of both the disease and treatment; and the complex field involving the development, approval and regulatory aspects of new treatment strategies. It stimulates readers to develop new and refreshing concepts that, in turn, could lead to cures and enhanced quality of life for children and adults suffering from acute leukemias. The book contains over 40 tables and over 220 illustrations, histologic photomicrographs, flow diagrams, graphs, and schemata with detailed figure legends. The result is a visually engaging book that is easy to read, review, and remember. The book also provides helpful and evidence-based treatment recommendations when providing induction therapy, consolidation therapy, and bone marrow transplantation.

This book demonstrates a logical approach to the nervous system that should serve the student throughout medical school rotations, postgraduate residency training, and medical practice during the lifelong learning task of evaluating patients with neurological problems. After a brief introduction to the concept of localization, Chapter 2 of the book deals with the brain and spinal cord of the central nervous system (CNS). The brain includes the cerebrum, cerebellum, and brainstem, and is organized into the four lobes of each cerebral hemisphere, plus the basal ganglia, thalamus and hypothalamus (diencephalon), brainstem, and cerebellum. Chapter 3 discusses the function of peripheral nerves and cardinal signs of peripheral nerve disease such as weakness, wasting and areflexia, and reviews the anatomical organization of peripheral nervous system (PNS). The fourth chapter includes special applications of neuro-logic covering coma, epilepsy, movement, vertigo, cord compression, and autonomics. The autonomic nervous system (ANS) enables, modulates, and controls the automatic functions we take for granted during day-to-day life until something goes awry. Chapter 6 focuses on the frontal lobe and associated subcortical structures that are the areas most involved in the pathogenesis of many psychiatric syndromes. The neurological examination is designed to assist with the localization of a patient’s disturbance affecting the nervous system. The exam consists of examination of mental status, cranial nerves, and that of other elements, namely motor, sensory and reflexes.