This second edition of Pocket Guide to Radiation Oncology provides an updated and rapid review of the existing standard of care and the most relevant literature. Like the first edition, this quick pocket-sized reference can be carried for a quick review instead of heavy textbooks often filled with esoteric topics and lengthy minutiae. The book has new chapters on the growing areas of oligometastatic disease, benign indications, and proton therapy. The book comprises 55 chapters organized by site-specific diseases: central nervous system neoplasms, head and neck cancers, thoracic cancers, breast cancer, gastrointestinal cancers, gynecologic cancers, genitourinary cancers, lymphoma, sarcoma, skin cancers, pediatric malignancies, metastatic disease, and benign indications. The chapters present must-know key points, including treatment options by stage, technical considerations, and important items for follow-up. Clinical pearls and tables covering treatment options, dose constraints, side effects, target delineations, and treatment planning complete each chapter. The chapters conclude with a list of selected, summarized studies relevant to the disease. The book takes an efficient and no-frills approach to fundamental topics in the field, making it the perfect reference for a quick review for the board exam or MOC and even serving as a handy reference during a case review at a tumor board. The book provides essential, quick reference appendices on radiation therapy symptom management, normal tissue tolerance constraints, and radiation therapy and new systemic agents.