This chapter provides information on some substances that are not exactly “pills” but they are often marketed as sleep aids. They include over-the-counter products, natural health products including herbal remedies, and cannabis. Over-the-counter sleep aids do not require a prescription and they are quite widely available through pharmacies. If a person has seasonal allergies, these medications may help them sleep on those nights when their allergy symptoms would otherwise disturb their sleep. Natural health products may help induce sleepiness and help some people who have mild difficulty falling asleep, and who are otherwise healthy (having no medical or mental health problems). There are several downsides of using recreational cannabis for sleep. Regular use of any form of cannabis can lead to dependence and difficult withdrawal symptoms including irritability, insomnia, depression and anxiety. Importantly, it can impair brain function, especially in people under age 21, whose brains are still developing.