This chapter describes the components of a professional practice model (PPM) implementation plan. Planning, selecting strategies, and ensuring accountability for PPM implementation requires a working group of diverse nursing professionals from multiple levels of a health system to fully capture their expertise and insights. The chapter reviews the steps of the implementation process and provides examples of a strengths, weaknesses, and opportunities/threats (SWOT) analysis, broad goal statements, and measurable objectives. It demonstrates the distinction between goals and objectives and suggests criteria for selecting among many implementation strategies. The chapter explores several implementation strategies: such as education, modification of work roles, workflow redesign, effective communication, and ongoing support and enrichment. It explains accountability for the plan’s implementation in terms of assigning responsibility, prioritizing goals, and setting realistic time frames for completion. Finally, the chapter presents the key success factors, including an optimistic leadership tone.