This chapter covers the question of what is culture, how to create an ideal meeting space, and the areas of consideration when coaching and managing from this perspective. For a successful relationship to begin and ultimately thrive across cultures, there are three equally important ingredients: safety, trust, and presence (STP). All factors are interdependent—each can only happen when the other two are present. This applies to one-on-one relationships or partnerships, work groups, and social engagements. These elements are even more important when people of different backgrounds come together. In a coaching relationship, the Coaching Core Competencies offer a rich coaching structure or framework for achieving STP. The areas of consideration discussed include immigrants, expatriates, refugees, third culture kids, cross-cultural people, language, cross-cultural communication, workplace, and location.