Children and teens with anxiety disorders share some common patterns in their thinking and response. They share core difficulties in accurately appraising specific situations, experiences, and other stimuli. Enhancing self-regulation, that is, shifting one’s attention in order to control and modulate one’s psychophysiological reactivity, emotions, thoughts, and behavior leads to various, individualized goals for treating anxious youth with hypnosis, cognitive behavioral therapy (CBT), and other mind-body approaches. Chronic childhood anxiety, the earliest and most frequent mental disorder among youth, has a potentially lifelong negative impact on self-regulation, learning, memory, and social behavior. Despite the dearth and variable quality of research, hypnosis offers a valuable adjunct to psychological interventions in the treatment of childhood anxiety, presenting as anxiety disorders, anticipatory and medical procedural anxiety, primary care presentations, or “normal nervous” responses to developmentally based situational stressors.