In recent years, the United States and many other countries have seen radical changes in both cultural and social acceptance of same-sex couples and sexual minorities. Increases in legal recognition of same-sex relationships have also changed the expectation for parenthood among sexual minorities. Although lesbian, gay, bisexual, and transgender (LGBT) persons and heterosexuals share many fertility and reproductive care-related concerns, sexual minorities often face unique challenges in the fertility care landscape. This chapter focuses on sexual minority women’s (SMW) experiences with fertility including the decision-making process to have children, deciding which medically assisted reproduction (MAR) method to use, issues surrounding choosing sperm donors, experiences in health care settings and interacting with fertility and reproduction care providers, and fertility outcomes. Advances in MAR methods have increased the number of methods from which SMW may choose to become parents, including vaginal insemination, intrauterine insemination, and in vitro fertilization (IVF).