Flood’s Successful Aging theory (Flood, 2005) was integrated with a sociocultural and biosocial model of successful aging related to self-care. A correlational design was used to quantify successful aging and explain the relationships between successful aging, global self-esteem, and sexual quality of life of community-based postmenopausal women. A nonrandom sample of 99 postmenopausal women completed the Successful Aging Inventory (Flood, 2005), the Rosenberg Self-Esteem Scale (Rosenberg, 1979), and the Sexual Quality-of-Life instrument (Symonds, Boolell, & Quirk, 2005). A significant correlation between successful aging, global self-esteem, and sexual quality of life was noted. Successful aging and meaning in life exists in postmenopausal women.