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Abstract
FORTY TO 80 PERCENT OF VERY LOW birth weight (VLBW) (infants <1,500 g) and extremely low birth weight (ELBW) (infants <1,000 g) infants will develop hyperglycemia when provided with glucose infusions adequate to meet basal metabolic needs.1,2 Avoiding hyperglycemia while providing adequate nutrition to promote growth and development is a major challenge for health care providers in the NICU. Some health care providers suggest that the judious use of continuous insulin infusion (CII) may provide the opportunity for increasing nutritional support while maintaining euglycemia. A systematic review of the literature is presented to evaluate the evidence supporting this practice.
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