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Abstract

Six randomized controlled trials (RCTs) investigated the efficacy of eye movement desensitization and reprocessing (EMDR) therapy for adults with anxiety disorders over a span of 20 years (1997–2017). Three RCTs focused on panic disorder, with or without agoraphobia (PDA); two studies targeted specific phobias, whereas the dependent variable of another RCT was “self-esteem,” considered as a mediator factor for anxiety disorders. In four RCTs, EMDR therapy demonstrated a positive effect on panic and phobic symptoms, whereas one RCT on PDA was partly negative and one study failed in improving self-esteem in patients with anxiety disorders. Considered as a whole, these preliminary data suggest EMDR therapy may be effective not only for PD but also for specific phobias. Further controlled studies are needed to corroborate these findings and also to systematically evaluate the efficacy of EMDR therapy for generalized anxiety disorder, social anxiety, and agoraphobia. Because cognitive behavioral therapy (CBT) is presently considered a first-line treatment for anxiety disorders, controlled comparisons between EMDR therapy and CBT would be especially useful in future investigations of EMDR treatment of anxiety disorders.

Tables

TABLE 1.
Randomized Controlled Trials That Have Investigated the Efficacy of EMDR Therapy for Anxiety Disorders in Adults
Author (Year)DiagnosisNControl ConditionNumber of SessionsStandard Protocol/VariationsFindings
Feske & Goldstein (1997)Panic disorder with agoraphobia (DSM-IV-TR)43WL or EFER6EMDREMDR > WL; EMDR > EFER on two of five primary measures. Not significant at 3-month follow-up.
Goldstein et al. (2000)Panic disorder with agoraphobia (DSM-IV-TR)46WL or ART6EMDREMDR > WL on panic/agoraphobia severity but not on frequency of panic attacks.

EMDR = ART. Stable at 1-month follow-up.
Horst et al. (2017)Panic disorder

(DSM-5)
84CBT13EMDR (audio tones)EMDR = CBT on ACQ, BSQ and QOL while MI was inconclusive.

Significant at 3-month follow-up.
Doering et al. (2013)Dental phobia

(DSM-IV-TR)
31WL3EMDREMDR>WL for reductions of dental anxiety and avoidance behavior. Significant at 3- and 12-month follow-up.
Triscari et al. (2015)Flying anxiety

(DSM-5)
65CBT-SD or

CBT-VRET
10CBT+EMDRCBT + EMDR = CBT + SD = CBT + VRET for decrease of flight anxiety. Significant at 1-year follow-up.
Staring et al. (2016)Anxiety disorders

(DSM-5)
47COMET6EMDREMDR < COMET in improving self-esteem. EMDR reduces COMET effects but not vice versa.

Note. ACQ = Agoraphobic Cognitions Questionnaire; ART = Association and Relaxation Therapy; BSQ = Body Sensations Questionnaire; CBT = cognitive behavioral therapy; CBT + EMDR= CBT combined with EMDR; CBT + VRET = CBT combined with VRET; COMET = Competitive Memory Training; EFER = Eye Fixation Exposure and Reprocessing; CBT + SD = CBT combined with systematic desensitization; DSM = Diagnostic and Statistical Manual of Mental Disorders; MI = Mobility Inventory; QOL= quality of life; VRET = virtual reality exposure therapy.

>indicates significantly better than; <indicates significantly worse than.

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